| Identification | More | [Name]
D-2-Phenylglycine | [CAS]
875-74-1 | [Synonyms]
D-(-)-2-PHENYLGLYCINE
D-2-PHENYLGLYCINE
D-(-)-A-AMINOPHENYLACETIC ACID
D(-)-ALPHA-AMINOPHENYLACETIC ACID
D-ALPHA-AMINOPHENYLACETIC ACID
(-)-D-ALPHA-PHENYLGLYCINE
D(-)-ALPHA-PHENYLGLYCINE
D-ALPHA-PHENYLGLYCINE
D-AMINOPHENYLACETIC ACID
D-(-)-A-PHENYLAMINOACETIC ACID
D-(-)-A-PHENYLGLYCINE
D-(-)-PHENYLGLYCINE
D-PHENYLGLYCINE
H-D-(PHENYL)GLY-OH
H-D-PHG-OH
PHENYLGLYCINE-D
(R)-(-)-2-PHENYLGLYCINE
(R)-(-)-ALPHA-AMINOPHENYLACETIC ACID
(R)-ALPHA-AMINOPHENYLACETIC ACID
(R)-(-)-ALPHA-PHENYLAMINOACETIC ACID | [EINECS(EC#)]
212-876-3 | [Molecular Formula]
C8H9NO2 | [MDL Number]
MFCD00008061 | [Molecular Weight]
151.16 | [MOL File]
875-74-1.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
302 °C (dec.)(lit.)
| [alpha ]
-156 º (c=1,1N HCl) | [Boiling point ]
273.17°C (rough estimate) | [density ]
1.2 g/cm3 (20℃) | [vapor pressure ]
0Pa at 25℃ | [refractive index ]
-158 ° (C=1, 1mol/L HCl) | [Fp ]
150 °C | [storage temp. ]
Store at RT. | [solubility ]
Aqueous Acid (Sparingly), Water (Slightly, Heated) | [form ]
Crystalline Powder | [pka]
1.94±0.10(Predicted) | [color ]
White | [optical activity]
[α]20/D 155°, c = 1 in 1 M HCl | [Water Solubility ]
0.3g/100mL | [Merck ]
14,7291 | [BRN ]
2208676 | [LogP]
-1.76 at 20℃ | [CAS DataBase Reference]
875-74-1(CAS DataBase Reference) | [NIST Chemistry Reference]
d a-Phenylglycine(875-74-1) | [EPA Substance Registry System]
875-74-1(EPA Substance) |
| Questions And Answer | Back Directory | [Description]
L-phenylglycine (Cephalexin EP Impurity A) is a derivative of glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in the spinal cord and an allosteric modulator of NMDA receptors. | [Storage]
Store at room temperature. Store in cool dry place in tightly closed container. Store away from oxidizing agent. |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29224995 |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Uses]
D-(-)-2-Phenylglycine is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA r
eceptors. | [Definition]
ChEBI: The R stereoisomer of alpha-phenylglycine. | [Flammability and Explosibility]
Nonflammable | [Synthesis]
Industrially, dphenylglycine
has been produced by a conventional
resolution method or by kinetic resolution
with acylase. Another enzymatic procedure has
been developed by Yamada et al. ,
as shown below.
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