| Identification | Back Directory | [Name]
indomethacin farnesil | [CAS]
85801-02-1 | [Synonyms]
IM-F
E-0710
Infree
Infree S
indomethacin farnesil
-5-methoxy-2-methyl-1H-indol-3-yl)
3,7,11-Trimethyldodeca-2,6,10-trien-1-yl 2-(1-(4-chlorobenzoyl)
3,7,11-TriMethyldodeca-2,6,10-trien-1-yl 2-(1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-1H-indol-3-yl)acetate
1-(4-Chlombenzoyl)-5-methoxy-2-methyl-1-indole-3-acetic acid3，7，11-trimethyl-2，6，10-dodecanetriene ester
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 3,7,11-trimethyl-2,6,10-dodecatrienyl ester
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 3,7,11-trimethyl-2,6,10-dodecatrien-1-yl ester | [Molecular Formula]
C34H40CINO4 | [MDL Number]
MFCD00870661 | [MOL File]
85801-02-1.mol | [Molecular Weight]
562.14 |
| Hazard Information | Back Directory | [Chemical Properties]
Acute toxicity LD50 mice, rats, dogs (mg/kg): 6800～7800, 1680～2000, >3000 orally. | [Uses]
Indomethacin farnesil is a new type of non-steroidal anti-inflammatory analgesic that is well distributed in inflammatory tissues. It is suitable for rheumatoid arthritis, osteoarthritis, low back pain, periarthritis of the shoulder and shoulder and neck, shoulder and arm syndrome. | [Definition]
ChEBI:Indomethacin farnesil is a N-acylindole. | [Synthesis]
After indomethacin is chlorinated with thionyl chloride, it reacts with 3,7,1-trimethyl-2,6,10-dodecatrienol in tetrahydrofuran solution in the presence of triethylamine to form indomethacin farnesil. |
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TCI Europe
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320-37350700 |
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https://www.tcichemicals.com/de/de/index.html |
| Company Name: |
TCI AMERICA
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800-4238616 |
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https://www.tcichemicals.com/en/us/index.html |
| Company Name: |
TCI Chemicals
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www.tcichemicals.com |
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