| Identification | More | [Name]
L(+)-Lactic acid | [CAS]
79-33-4 | [Synonyms]
2-HYDROXYPROPIONIC ACID
L-(+)-2-HYDROXYPROPANOIC ACID
L-2-HYDROXYPROPIONIC ACID
LACTIC ACID
L(+)-LACTIC ACID
L-LACTIC ACID
L-(+)-MILK ACID
PURAC(R) 50
PURAC(R) HQ 88
PURAC(R) HS 88
PURAC(R) PF 88
PURAC(R) SP 80
PURAC(R) SP 88
(S)-(+)-2-HYDROXYPROPANOIC ACID
(S)-2-HYDROXYPROPIONIC ACID
SARCOLACTIC ACID
(S)-(+)-LACTIC ACID
(+)-Milchsαure
(S)-Milchsαure
2-hydroxy-,(S)-Propanoicacid | [EINECS(EC#)]
201-196-2 | [Molecular Formula]
C3H6O3 | [MDL Number]
MFCD00064266 | [Molecular Weight]
90.08 | [MOL File]
79-33-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
52-54°C | [alpha ]
-13.5 º (c=2.5, 1.5N NaOH) | [Boiling point ]
125 °C
| [density ]
1.206 g/mL at 25 °C
| [vapor pressure ]
0.038Pa at 25℃ | [FEMA ]
2611 | LACTIC ACID | [refractive index ]
n20/D 1.427
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
H2O: 10 mg/mL, clear, colorless
| [form ]
Powder/Solid | [pka]
pK at 25°, 3.79 | [color ]
White | [Odor]
odorless acidic | [Odor Type]
odorless | [optical activity]
[α]20/D 13.5°, c = 2.5 in 1.5 M NaOH | [Water Solubility ]
SOLUBLE | [Sensitive ]
Hygroscopic | [Usage]
Occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, | [JECFA Number]
930 | [Merck ]
14,5337 | [BRN ]
1720251 | [InChIKey]
JVTAAEKCZFNVCJ-REOHCLBHSA-N | [LogP]
-0.54 at 20℃ | [CAS DataBase Reference]
79-33-4(CAS DataBase Reference) | [NIST Chemistry Reference]
(s)-2-Hydroxypropanoic acid(79-33-4) | [EPA Substance Registry System]
79-33-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,C | [Risk Statements ]
R38:Irritating to the skin.
R41:Risk of serious damage to eyes.
R34:Causes burns.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing . | [RIDADR ]
3261 | [WGK Germany ]
1
| [RTECS ]
OD2800000
| [F ]
3-10 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29181100 | [Toxicity]
LD50 intraperitoneal in mouse: 3194mg/kg |
| Questions And Answer | Back Directory | [Background]
L-Lactic acid (L(+)-Lactic Acid) is the optically active form of lactic acid and has an (S) stereochemical arrangement. L-Lactic Acid was first registered as a pesticide 1988 as a plant-growth regulator. There are currently no L-Lactic Acid end-use pesticide products for use as a plant growth regulator. Animals produce L-Lactate, the conjugate base of lactic acid, from pyruvate via lactate dehydrogenase in fermentation during normal metabolism and exercise. Lactic acid bacteria perform lactic acid fermentation, converting carbohydrates to lactic acid. In humans, lactic acid and its conjugate base are part of many biological processes, from prenatal development to extracellular fluid surrounding neurons. L(+)-lactic acid is a colourless to yellowish, nearly odourless, syrupy liquid with a mild acid taste. It is commercially available as aqueous solutions of various concentrations. These solutions are stable under normal storage conditions.Lactic acid is nontoxic to humans and the environment, but concentrated solutions can cause skin irritation and eye damage. Thus, they must be labelled with a hazard pictogram and related statements. Lactic acid is readily biodegradable.
|
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and o | [Definition]
ChEBI: An optically active form of lactic acid having (S)-configuration. | [General Description]
L-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactis produces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81). | [Flammability and Explosibility]
Notclassified | [Biochem/physiol Actions]
L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase. | [storage]
Store at 4°C, sealed storage, away from moisture | [Purification Methods]
Purify lactic acid by fractional distillation at 0.1mm pressure, followed by fractional crystallisation from diethyl ether/isopropyl ether (1:1, dried with sodium). [Borsook et al. J Biol Chem 102 449 1933.] The solvent mixture, *benzene/diethyl ether (1:1) containing 5% pet ether (b 60-80o) has also been used. [Brin Biochemical Preparations 3 61 1953, Beilstein 3 IV 633.] |
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