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ChemicalBook--->CAS DataBase List--->756526-06-4

756526-06-4

756526-06-4 Structure

756526-06-4 Structure
IdentificationBack Directory
[Name]

H2N-PEG8-tBu
[CAS]

756526-06-4
[Synonyms]

756526-06-4
H2N-PEG8-tBu
Amino-PEG8-Boc
Amino-PEG8-COOtBu
H2N-PEG8-CH2CH2COOtBu
NH2-PEG8-CH2CH2COOtBu
Amino-PEG8-t-butyl ester
Amino-PEG9-t-butyl ester
amino-dPEG8.(TM).-t-butyl ester
NH2-PEG8-t-butyl ester,Amino-PEG8-t-butyl ester
tert-butyl 1-amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
H2N-PEG8-CH2CH2COOtBu
27-Amino-4,7,10,13,16,19,22,25-octaoxaheptacosanoic acid 1,1-dimethylethyl ester
4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-amino-, 1,1-dimethylethyl ester
[Molecular Formula]

C23H47NO10
[MDL Number]

MFCD11041142
[MOL File]

756526-06-4.mol
[Molecular Weight]

497.62
Chemical PropertiesBack Directory
[Boiling point ]

544.3±45.0 °C(Predicted)
[density ]

1.067±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

Soluble in Water, DMSO, DCM, DMF
[form ]

Oil
[pka]

8.74±0.10(Predicted)
[color ]

Colorless to light yellow
[InChI]

InChI=1S/C23H47NO10/c1-23(2,3)34-22(25)4-6-26-8-10-28-12-14-30-16-18-32-20-21-33-19-17-31-15-13-29-11-9-27-7-5-24/h4-21,24H2,1-3H3
[InChIKey]

UMJVFHNJPJVDSB-UHFFFAOYSA-N
[SMILES]

C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[HS Code ]

2942000090
Hazard InformationBack Directory
[Description]

Amino-PEG8-t-butyl ester is a monodisperse PEG linker containing an amino group with a t-butyl protected carboxyl group.The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
[Uses]

H2N-PEG8-tBu is a cleavable 8-unit PEG-ADC linker for antibody drug conjugate (ADC) synthesis.
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