Identification | Back Directory | [Name]
H2N-PEG8-tBu | [CAS]
756526-06-4 | [Synonyms]
756526-06-4 H2N-PEG8-tBu Amino-PEG8-Boc Amino-PEG8-COOtBu H2N-PEG8-CH2CH2COOtBu NH2-PEG8-CH2CH2COOtBu Amino-PEG8-t-butyl ester Amino-PEG9-t-butyl ester amino-dPEG8.(TM).-t-butyl ester NH2-PEG8-t-butyl ester,Amino-PEG8-t-butyl ester tert-butyl 1-amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate H2N-PEG8-CH2CH2COOtBu 27-Amino-4,7,10,13,16,19,22,25-octaoxaheptacosanoic acid 1,1-dimethylethyl ester 4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-amino-, 1,1-dimethylethyl ester | [Molecular Formula]
C23H47NO10 | [MDL Number]
MFCD11041142 | [MOL File]
756526-06-4.mol | [Molecular Weight]
497.62 |
Chemical Properties | Back Directory | [Boiling point ]
544.3±45.0 °C(Predicted) | [density ]
1.067±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Oil | [pka]
8.74±0.10(Predicted) | [color ]
Colorless to light yellow | [InChI]
InChI=1S/C23H47NO10/c1-23(2,3)34-22(25)4-6-26-8-10-28-12-14-30-16-18-32-20-21-33-19-17-31-15-13-29-11-9-27-7-5-24/h4-21,24H2,1-3H3 | [InChIKey]
UMJVFHNJPJVDSB-UHFFFAOYSA-N | [SMILES]
C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN |
Hazard Information | Back Directory | [Description]
Amino-PEG8-t-butyl ester is a monodisperse PEG linker containing an amino group with a t-butyl protected carboxyl group.The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. | [Uses]
H2N-PEG8-tBu is a cleavable 8-unit PEG-ADC linker for antibody drug conjugate (ADC) synthesis. |
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