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ChemicalBook--->CAS DataBase List--->872679-70-4

872679-70-4

872679-70-4 Structure

872679-70-4 Structure
IdentificationBack Directory
[Name]

Fmoc-9-Amino-4,7-Dioxanonanoic acid
[CAS]

872679-70-4
[Synonyms]

Fmoc-AEEP
Fmoc-PEG2- CH2CH2COOH
Fmoc-N-amido-PEG2-acid
FMoc-NH-PEG2-CH2CH2COOH
Fmoc-PEG2-propionic acid
Fmoc-AEEP-OH≥ 98% (HPLC)
Fmoc-N-amido-PEG2-acid 99%
Fmoc-9-amino-4,7-dioxonanoic acid
9-(Fmoc-amino)-4,7-dioxanonanoic Acid
3-[2-[2-(Fmoc-amino)ethoxy]ethoxy]propionic Acid
9-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4,7-dioxanonanoic Acid
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oic acid
4,7,12-Trioxa-10-azatridecanoic acid, 13-(9H-fluoren-9-yl)-11-oxo-
9-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-4,7-dioxanonanoicAcid>
2,7,10-Trioxa-4-azatridecan-13-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
3-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]propanoic acid
3-[2-[2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]ethoxy]ethoxy]propionic Acid
3-[2-[2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]ethoxy]ethoxy]propanoic acid
[Molecular Formula]

C22H25NO6
[MDL Number]

MFCD08064306
[MOL File]

872679-70-4.mol
[Molecular Weight]

399.437
Chemical PropertiesBack Directory
[Melting point ]

95.0 to 99.0 °C
[Boiling point ]

621.0±50.0 °C(Predicted)
[density ]

1.243±0.06 g/cm3 (20 ºC 760 Torr)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

soluble in Methanol
[form ]

powder to crystal
[pka]

4.28±0.10(Predicted)
[color ]

White to Almost white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P302+P352-P362+P364
Hazard InformationBack Directory
[Description]

Fmoc-N-amido-PEG2-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
[Chemical Properties]

White crystalline powder
[Uses]

Fmoc-AEEP-OH is used in preparation of glucose-responsive insulin conjugates.
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