| Identification | More | [Name]
2-Bromopropane | [CAS]
75-26-3 | [Synonyms]
2-BROMOPROPANE
ISOPROPYL BROMIDE
2-bromo-propan
2-Brompropan
bromo-2propane
iso-C3H7Br
propane,2-bromo-
sec-Propyl bromide
sec-propylbromide
Iso-propyl bromide(2-bromopropane)
2-BROMOPROPANE, STANDARD FOR GC
2-BROMOPROPANE, 99+%
PropylBromide~98%
2-BromopropaneForSynthesis
2-Bromopropane, 98+%
ISOPROPYL BROMIDE pure | [EINECS(EC#)]
200-855-1 | [Molecular Formula]
C3H7Br | [MDL Number]
MFCD00000147 | [Molecular Weight]
122.99 | [MOL File]
75-26-3.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless liquid | [Melting point ]
-89 °C (lit.) | [Boiling point ]
59 °C (lit.) | [density ]
1.31 g/mL at 25 °C(lit.)
| [vapor pressure ]
224 hPa (20 °C) | [refractive index ]
n20/D 1.425(lit.)
| [Fp ]
67 °F
| [storage temp. ]
Flammables area | [solubility ]
3.18g/l | [form ]
Liquid | [color ]
Clear colorless to very light brown | [Stability:]
Stable. Flammable. Incompatible with strong oxidizing agents. | [explosive limit]
4.6%(V) | [Water Solubility ]
0.3 g/100 mL | [Merck ]
14,5210 | [BRN ]
741852 | [Dielectric constant]
9.4600000000000009 | [InChIKey]
NAMYKGVDVNBCFQ-UHFFFAOYSA-N | [Uses]
Synthesis of pharmaceuticals, dyes, other
organics. | [CAS DataBase Reference]
75-26-3(CAS DataBase Reference) | [NIST Chemistry Reference]
Propane, 2-bromo-(75-26-3) | [EPA Substance Registry System]
75-26-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,T | [Risk Statements ]
R60:May impair fertility.
R11:Highly Flammable.
R48/20:Harmful: danger of serious damage to health by prolonged exposure through inhalation .
R66:Repeated exposure may cause skin dryness or cracking. | [Safety Statements ]
S53:Avoid exposure-obtain special instruction before use .
S16:Keep away from sources of ignition-No smoking .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2344 3/PG 2
| [WGK Germany ]
1
| [RTECS ]
TX4111000
| [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29033036 | [Safety Profile]
Moderately toxic by
intraperitoneal route. A very flammable
liquid and dangerous fire hazard. When
heated to decomposition it emits toxic
fumes of Br-. See also BROMIDES. | [Hazardous Substances Data]
75-26-3(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Description]
2-Bromopropane, also known as isopropyl bromide and 2-propyl bromide, is the halogenated hydrocarbon with the formula CH3CHBrCH3. It is a colorless liquid. It is used for introducing the isopropyl functional group in organic synthesis. 2-Bromopropane is prepared by heating isopropanol with hydrobromic acid. | [Chemical Properties]
colourless liquid | [Preparation]
2-Bromopropane is commercially available. It may be prepared in the ordinary manner of alkyl bromides, by reacting isopropanol with phosphorus and bromine, or with phosphorus tribromide. | [Health Hazard]
2-bromopropane, apparently caused ovarian failure, azoospermia, oligospermia, and anemia in a group of Korean workers. Experimental studies confirm specific reproductive effects in females and males. Hematopoietic effects and peripheral neuropathy also have been reported in animal studies. There is limited evidence of adverse effects in exposed workers similar to those seen in animals. | [Purification Methods]
Wash the bromide with 95% H2SO4 (concentrated acid partially oxidised it) until a fresh portion of acid did not become coloured after several hours, then with water, aqueous NaHSO3, aqueous 10% Na2CO3 and again with water. (The H2SO4 can be replaced by conc HCl.) Prior to this treatment, isopropyl bromide has been purified by bubbling a stream of oxygen containing 5% ozone through it for 1hour, followed by shaking with 3% hydrogen peroxide solution, neutralising with aqueous Na2CO3, washing with distilled water and drying. Alternatively, it has been treated with elemental bromine and stored for 4 weeks, then extracted with aqueous NaHSO3 and dried with MgSO4. After the acid treatment, isopropyl bromide can be dried with Na2SO4, MgSO4 or CaH2, and fractionally distilled. [Beilstein 1 IV 208.] |
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