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ChemicalBook--->CAS DataBase List--->74389-68-7

74389-68-7

74389-68-7 Structure

74389-68-7 Structure
IdentificationBack Directory
[Name]

Platelet Activating Factor-16
[CAS]

74389-68-7
[Synonyms]

PAF
ACGEPC
C16PAF
PAF (C16)
C16-02:0 PC
PAF (C16),99%
C16-PAF-acether
C16 ENANTIOMERIC PAF
PLATELET ACTIVATING FACTOR
PLATELET ACTIVATING FACTOR-16
PLATELET ACTIVATING FACTOR (C16)
Blood platelet-activating factor acether
1-HEXADECYL-2-ACETYL-SN-GLYCERO-3- &
PAF[C16] (PLATELET ACTIVATING FACTOR [C1 6])
1-ALKYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1-hexadecyl-2-acetyl-glycero-3-phosphocholine
1-O-AKYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
β-acetyl-γ-o-hexadecyl-l-α-phosphatidylcholine
3-sn-Phosphatidylcholine, 1-hexadecyl-2-acetyl
2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine
1-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine
1-O-PALMITYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1-O-HEXADECYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
3-O-HEXADECYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
L-A-PHOSPHATIDYLCHOLINE, B-ACETYL-*GAMMA -O-HEXADECY
1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate
L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-ALKYL
1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-HEXADECYL
PAF (C16)1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine
Platelet Activating Factor-16 - CAS 74389-68-7 - Calbiochem
1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate
1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE;C16-02:0 PC
L-alpha-phosphatidylcholine-beta-acetyl-gamma-o-hexadecylhygroscopic
(R)-2-Acetoxy-3-(hexadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
(7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide
1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine, 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1-hexadecyl-2-acetyl, PAF(C16), Platelet activating factor, 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate
[Molecular Formula]

C26H54NO7P
[MDL Number]

MFCD00043214
[MOL File]

74389-68-7.mol
[Molecular Weight]

523.68
Chemical PropertiesBack Directory
[Melting point ]

247 °C
[storage temp. ]

-20°C
[solubility ]

Soluble in H2O or ethanol
[form ]

lyophilized powder
[color ]

White to off-white
[Water Solubility ]

Soluble to 100 mM in water
[BRN ]

3574588
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22-38-40-48/20/22
[Safety Statements ]

36/37-24/25-22
[RIDADR ]

UN 1888 6.1/PG 3
[WGK Germany ]

3
[RTECS ]

EC6060000
[F ]

10-21
Hazard InformationBack Directory
[Uses]

C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. It may also be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.
[Uses]

PAF (C16) (cas# 74389-68-7) is a blood platelet-activating factor, used to study human airway smooth muscle cell line.
[Definition]

ChEBI: A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.
[General Description]

C16-02:0 PC, also known as 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16 PAF) (acetyl PAF), is a platelet-activating factor (PAF). Acetyl PAF is present in the body and it contains ether-linked hexadecyl chain at the sn-1 position and an acetyl group at the sn-2 position.
[Biological Activity]

Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.
[Biochem/physiol Actions]

Platelet-activating factor (PAF) is a pro-inflammatory agent that exhibits variety of biological and pharmacological effects. It plays a major role in initiation and progression of atherosclerosis. PAF acts as a potential biomarker for coronary artery diseases. It yields LysoPAF (1-O-alkyl-2-hydroxy-sn-glycero-3-phosphocholine) on hydrolysis by platelet-activating factor-acetylhydrolase.
[storage]

Store at -20°C
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