Identification | Back Directory | [Name]
Platelet Activating Factor-16 | [CAS]
74389-68-7 | [Synonyms]
PAF ACGEPC C16PAF PAF (C16) C16-02:0 PC PAF (C16),99% C16-PAF-acether C16 ENANTIOMERIC PAF PLATELET ACTIVATING FACTOR PLATELET ACTIVATING FACTOR-16 PLATELET ACTIVATING FACTOR (C16) Blood platelet-activating factor acether 1-HEXADECYL-2-ACETYL-SN-GLYCERO-3- & PAF[C16] (PLATELET ACTIVATING FACTOR [C1 6]) 1-ALKYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-hexadecyl-2-acetyl-glycero-3-phosphocholine 1-O-AKYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE β-acetyl-γ-o-hexadecyl-l-α-phosphatidylcholine 3-sn-Phosphatidylcholine, 1-hexadecyl-2-acetyl 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine 1-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine 1-O-PALMITYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-HEXADECYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 3-O-HEXADECYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE L-A-PHOSPHATIDYLCHOLINE, B-ACETYL-*GAMMA -O-HEXADECY 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-ALKYL 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-HEXADECYL PAF (C16)1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine Platelet Activating Factor-16 - CAS 74389-68-7 - Calbiochem 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE;C16-02:0 PC L-alpha-phosphatidylcholine-beta-acetyl-gamma-o-hexadecylhygroscopic (R)-2-Acetoxy-3-(hexadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate (7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine, 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1-hexadecyl-2-acetyl, PAF(C16), Platelet activating factor, 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate | [Molecular Formula]
C26H54NO7P | [MDL Number]
MFCD00043214 | [MOL File]
74389-68-7.mol | [Molecular Weight]
523.68 |
Chemical Properties | Back Directory | [Melting point ]
247 °C | [storage temp. ]
-20°C | [solubility ]
Soluble in H2O or ethanol | [form ]
lyophilized powder
| [color ]
White to off-white | [Water Solubility ]
Soluble to 100 mM in water | [BRN ]
3574588 |
Hazard Information | Back Directory | [Uses]
C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. It may also be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E. | [Uses]
PAF (C16) (cas# 74389-68-7) is a blood platelet-activating factor, used to study human airway smooth muscle cell line. | [Definition]
ChEBI: A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis. | [General Description]
C16-02:0 PC, also known as 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16 PAF) (acetyl PAF), is a platelet-activating factor (PAF). Acetyl PAF is present in the body and it contains ether-linked hexadecyl chain at the sn-1 position and an acetyl group at the sn-2 position. | [Biological Activity]
Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability. | [Biochem/physiol Actions]
Platelet-activating factor (PAF) is a pro-inflammatory agent that exhibits variety of biological and pharmacological effects. It plays a major role in initiation and progression of atherosclerosis. PAF acts as a potential biomarker for coronary artery diseases. It yields LysoPAF (1-O-alkyl-2-hydroxy-sn-glycero-3-phosphocholine) on hydrolysis by platelet-activating factor-acetylhydrolase. | [storage]
Store at -20°C |
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