| Identification | More | [Name]
2-Pyrrolidinoethyl chloride hydrochloride | [CAS]
7250-67-1 | [Synonyms]
1-(2-CHLOROETHYL)PYRROLIDINE HCL
1-(2-CHLOROETHYL)PYRROLIDINE HYDROCHLORIDE
2-CHLOROETHYLPYRROLIDINE HCL
2-CHLOROETHYLPYRROLIDINE HYDROCHLORIDE
2-PYRROLIDINOETHYL CHLORIDE HYDROCHLORIDE
N-(2-CHLOROETHYL)PYRROLIDINE HYDROCHLORIDE
N-(BETA-CHLOROETHYL)PYRROLIDINE HCL
PYRROLIDINE, 1-(2-CHLOROETHYL)-, HYDROCHLORIDE
PYRROLIDINOETHYL CHLORIDE HYDROCHLORIDE
1-(2-chloroethyl)-pyrrolidinhydrochloride
2-(N-Pyrrolidino)ethyl chloride hydrochloride
N-(2-Chloroethyl)pyrrolidine HCl
N-Chloroethylpyrprolidine
2-ChloroethylpyrrolidineHcl98%
2-Chloroethylpyrrolidine Hcl 98%
N-CHLOROETHYL PYRROLIDINE
2-Pyrrolidinoethyl
N-(2-Chloroethyl)pyrrolidine hydrochloride 98%
1-(2-Chloroethyl)pyrrolidine hydrochloride ,98%
1-(2-Chloroethyl)pyrrolidinium chloride | [EINECS(EC#)]
230-660-7 | [Molecular Formula]
C6H13Cl2N | [MDL Number]
MFCD00012718 | [Molecular Weight]
170.08 | [MOL File]
7250-67-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white to off-white crystals or crystalline powder | [Melting point ]
167-170 °C(lit.)
| [Boiling point ]
237°C(lit.) | [density ]
0.4[at 20℃] | [vapor pressure ]
1.64hPa at 25℃ | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Slightly), Water (Slightly) | [form ]
Crystalline Powder or Crystals | [color ]
White to off-white | [Water Solubility ]
Soluble | [Sensitive ]
Hygroscopic | [Detection Methods]
Titration,NMR | [BRN ]
3677061 | [InChI]
InChI=1S/C6H12ClN.ClH/c7-3-6-8-4-1-2-5-8;/h1-6H2;1H | [InChIKey]
FSNGFFWICFYWQC-UHFFFAOYSA-N | [SMILES]
N1(CCCl)CCCC1.[H]Cl | [LogP]
0.736 at 25℃ | [CAS DataBase Reference]
7250-67-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/22:Harmful by inhalation and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
UY0703150
| [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white crystals or crystalline powder | [Uses]
1-(2-Chloroethyl)pyrrolidine is a haloalkyl substituted pyrrolidine used in the preparation of various pharmaceutical compound such as the estrogen receptor antagonist Nafoxidine (N212800) and its ana
logues. | [Purification Methods]
Purify the hydrochloride by recrystallisation from isopropanol/di-isopropyl ether (charcoal) and recrystallise it twice more. The free base, b 55-56o/11mm, 60-63o/23mm and 90o/56mm, is relatively unstable and should be converted to the hydrochloride immediately, by dissolving in isopropanol and bubbling dry HCl through the solution at 0o, filtering off the hydrochloride and recrystallising it. The picrate has m 107.3-107.8o (from EtOH) [Cason J Org Chem 24 247 1959, Wright et al. J Am Chem Soc 70 3098 1948]. [Beilstein 20 III/IV 66.] |
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