Identification | Back Directory | [Name]
D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL | [CAS]
716-61-0 | [Synonyms]
levoamine Chloromycin base L-BASE (AMINODIOL) chloramphenicolbase CHLORAMPHENICOL-WATER SOLUBLE D(-)Threo-1-(4-nitro-phenyl)-2 CHLORAMPHENICOL BASE CRYSTALLINE (R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol (1R,2R)-1-(4-Nitrophenyl)-2-aminopropane-1,3-diol D-THREO-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANE (1R,2R)-2-AMINO-1-(4-NITROPHENOL)PROPANE-1,3-DIOL (1R,2R)-2-AMINO-1-(4-NITROPHENYL)PROPANE-1,3-DIOL (1R,2R)-(-)-2-AMINO-1-NITROPHENYL)-1,3-PROPANEDIOL 2-amino-1-(p-nitrophenyl)-3-propanediod-threo-(-)- D-(-)threo-2-amino-1-(p-nitrophenyl)propane-1,3-diol D(-)THREO-1-(4-NITRO-PHENYL)-2-AMINO-1,3-PROPANEDIOL d-threo-(-)-2-amino-1-(p-nitrophenyl)-1,3-propanediol D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL (1R,2R)-(-)-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL 1,3-Propanediol, 2-amino-1-(4-nitrophenyl)-, (1R,2R)- [1R,2R,(-)]-2-Amino-1-(p-nitrophenyl)-1,3-propanediol (1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol,96% (1R,2R)-(-)-2-AMINO-1-ITROPHENYL)-1,3-PR OPANEDIOL,99% (1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol 99% (1R,2R)-2-AMino-1-(4-nitrophenyl)propane-1,3-diol, 96% 5GR (1R,2R)-(-)-2-AMino-1-(4-nitrophenyl)-1,3-propanediol, 96%, 96% (1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol hydrochloride (1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol≥ 99% (by Assay) D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol Chloramphenicol base, D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol (1R,2R)-()-2-Amino-1-(4-nitrophenyl)-1,3-propanediol,D-()-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base | [EINECS(EC#)]
211-938-7 | [Molecular Formula]
C9H12N2O4 | [MDL Number]
MFCD00078126 | [MOL File]
716-61-0.mol | [Molecular Weight]
212.2 |
Chemical Properties | Back Directory | [Appearance]
light yellow powder | [Melting point ]
163-165 °C(lit.)
| [Boiling point ]
352.03°C (rough estimate) | [density ]
1.3136 (rough estimate) | [refractive index ]
-30.5 ° (C=1, 6mol/L HCl) | [storage temp. ]
−20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [Water Solubility ]
almost transparency in hot Water | [form ]
Powder | [pka]
10.98±0.45(Predicted) | [color ]
Light yellow | [optical activity]
[α]25/D 30°, c = 1 in 6 M HCl | [InChIKey]
OCYJXSUPZMNXEN-RKDXNWHRSA-N |
Hazard Information | Back Directory | [Chemical Properties]
light yellow powder | [Uses]
D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chloramphenicol (C325030), a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuel
ae. | [Uses]
Chloramphenicol base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol and is a degradation product commonly encountered with commercial production of chloramphenicol. Chloramphenicol base has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol. | [Definition]
ChEBI: A diol that is propane 1,3-diol bearing additional amino and 4-nitrophenyl substituents at positions 2 and 1 respectively. |
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