| Identification | Back Directory | [Name]
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline | [CAS]
694499-26-8 | [Synonyms]
PON50
SW-53
SWF-53
Ponatinib int2
Ponatinib Impurity 3
Pralsetinib Impurity 1
4-(4-Methylpiperazinomethyl)-3-
4-(4-Methylpiperazinomethyl)-4-(trifluoromethyl)aniline
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
1-[4-Amino-2-(Trifluoromethyl)benzyl]-4-MethylPiperazine
4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline-d8
4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)aniline
4-((4-Methylpiperazin-1-yl)methyl)-3-trifluoromethylphenylamine
Benzenamine, 4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoro...
3-(trifluoromethyl)-4-((4-methylpiperazin-1-yl)methyl)benzenamine
4-[(4-Methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzenamine
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline IN Stock
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline USP/EP/BP
4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline 95+%
4-(4-METHYLPIPERAZINOMETHYL)-3-(TRIFLUOROMETHYL)ANILINE 694499-26-8
BenzenaMine, 4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)-
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline TDS msds coa
4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline IN Stock COA TDS free sample
5-Amino-2-[(4-methylpiperazin-1-yl)methyl]benzotrifluoride, 1-[4-Amino-2-(trifluoromethyl)benzyl]-4-methylpiperazine
4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline
4-((4-Methylpiperazin-1-yl)methyl)-3-trifluoromethylphenylamine | [Molecular Formula]
C13H18F3N3 | [MDL Number]
MFCD00010635 | [MOL File]
694499-26-8.mol | [Molecular Weight]
273 |
| Chemical Properties | Back Directory | [Boiling point ]
329.1±42.0 °C(Predicted) | [density ]
1.227 | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [pka]
7.55±0.10(Predicted) | [InChI]
InChI=1S/C13H18F3N3/c1-18-4-6-19(7-5-18)9-10-2-3-11(17)8-12(10)13(14,15)16/h2-3,8H,4-7,9,17H2,1H3 | [InChIKey]
ZMWAZMYBMAAMAW-UHFFFAOYSA-N | [SMILES]
C1(N)=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1 |
| Hazard Information | Back Directory | [Uses]
4-(6-Acryloyloxyhexyloxy)-benzoesure (4-cyanophenylester) can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and in the process of chemical and pharmaceutical synthesis. | [Synthesis]
4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline Into a solution 4-methyl-1-(4-nitro-2-(trifluoromethyl)benzyl)piperazine (1.5 g, 5 mmol) in MeOH (250 mL) was added Raney Nickel (0.15 g, 10 wt %). The suspension was stirred under hydrogen atmosphere (50 psi) for 24 hrs and monitored by TLC. The reaction mixture was filtered through celite and the filtrate was concentrated under reduced pressure to yield the desired product (1.36 g, 100%). 1H NMR (300 MHz, CDCl3) |?: 7.43-7.46 (1H, d, J=9.0 Hz), 6.91 (1H, s), 6.77-6.80 (1H, d J=9.0 Hz), 3.77 (2H, s), 3.54 (2H, s), 2.53 (8H, brs), 2.34 (3H, s). | [storage]
Store long-term at 2-8°C.
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