| Identification | More | [Name]
5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine | [CAS]
68892-41-1 | [Synonyms]
5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE
5'-O-DIMETHOXYTRITYL-N-ISOBUTYRYL-DEOXYGUANOSINE
DMT-DG-IBU
DMT-N-IB-DG
DMT-NIBU-DG
IBU-DMT-DEOXYGUANOSINE
N2-ISOBUTYROYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE
N2-ISOBUTYRYL-5'-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE
N2-ISOBUTYRYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE
guanosine,5’-o-[bis(4-methoxyphenyl)phenylmethyl]-2’-deoxy-n-(2-methyl-1-oxopr
5'-O-[bis(4-methoxyphenyl)benzyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)guanosine
DMT-DG-(N-IBU)
5'-O-Dimethylterephthalate-N-isobutyryl-2'-deoxyguanosine
5'-O-DIMETHOXYTRITYL-N-ISOBUTYRYL-DEOXYGUANOSINE(DMT-DG-IBU)
5'-O-Dimethoxytrityl-N-BenzoylDeoxycytidine
ibu-dmt-dg
2'-Deoxy-5'-O-DMT-N2-Isobutyryl-D-guanosine
5''-O-DIMETHOXYTRITYL-N-ISO-BUTYRYLDEOXYGUANOSINE(DMT-BZ-DG)
Guanosine, 5'-O-[bis(4-methoxyphenyl) phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-
5''-O-(4,4''-Dimethoxytrityl)-N2-isobutyryl-2''-deoxyguanosine (synthetic) | [EINECS(EC#)]
272-615-4 | [Molecular Formula]
C35H37N5O7 | [MDL Number]
MFCD00010059 | [Molecular Weight]
639.7 | [MOL File]
68892-41-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
~150 °C (dec.)(lit.) | [Boiling point ]
671.92°C (rough estimate) | [density ]
1.2353 (rough estimate) | [refractive index ]
1.7500 (estimate) | [storage temp. ]
−20°C
| [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
9.16±0.20(Predicted) | [color ]
White | [Water Solubility ]
2.4mg/L at 20℃ | [InChIKey]
RMQXDNUKLIDXOS-PTIWCXHYNA-N | [SMILES]
C(OC[C@@H]1[C@@H](O)C[C@H](N2C=NC3C(=O)NC(NC(=O)C(C)C)=NC2=3)O1)(C1=CC=CC=C1)(C1C=CC(OC)=CC=1)C1=CC=C(OC)C=C1 |&1:3,4,7,r| | [LogP]
2.98 at 20℃ | [CAS DataBase Reference]
68892-41-1(CAS DataBase Reference) | [EPA Substance Registry System]
68892-41-1(EPA Substance) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
1-3-10 | [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Uses]
N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine can be used as fluorescent hydrogel with high intensity. | [Flammability and Explosibility]
Notclassified | [Synthesis]
2N-Isobutyryl deoxyguanosine (B5-I) was dried by co-evaporation with dry pyridine three times. To a stirred suspension of dry (B5-I) (14.15 mmol) in pyridine (100 mL), a solution of dimetoxytrityl chloride (14.8 mmol) in pyridine (30 mL) was added dropwise over 60 min. The reaction mixture was left for 4 h at room temperature, cooled to 0 C. by immersion in an ice water bath, quenched with 5% NaHCO3 (100 mL), and extracted with ethyl acetate (3×100 mL). The organic fractions were pooled, dried over magnesium sulfate, and concentrated in a vacuum, and the residue was co-evaporated with toluene. The gum oil residue was dissolved in a minimum amount of methylenechloride and added dropwise to a mixture of ethyl and petroleum ether (2000 mL 75/25) with stirring. After 20 min, pure 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine precipitated from the solution and was filtered off and dried. Yield: 75%
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