| Identification | More | [Name]
Glycine ethyl ester hydrochloride | [CAS]
623-33-6 | [Synonyms]
AMINO-ACETIC ACID ETHYL ESTER
AMINOACETIC ACID ETHYL ESTER HYDROCHLORIDE
ETHYL AMINOACETATE HCL
ETHYL AMINOACETATE HYDROCHLORIDE
ETHYL GLYCINATE HYDROCHLORIDE
GLYCINE ETHYL ESTER
GLYCINE ETHYL ESTER HCL
GLYCINE ETHYL ESTER HYDROCHLORIDE
GLYCINE-OET HCL
H-GLY-OET HCL
RARECHEM AL BW 0032
Glycineethylesterhydrochlor
Glycocollethylesterhydrochloride
usafdo-10
Ethyl glycinate hydrochloride~H-Gly-OEt.HCl
Ethyl Glycinate, HCl (1.00893)
Gly-OEt HCl
Glycineethylesterhydrochloride,99%
glycine ethyhydnchlordeester
Glycineethylester·HCl,Glycineethylesterhydrochloride | [EINECS(EC#)]
210-787-4 | [Molecular Formula]
C4H10ClNO2 | [MDL Number]
MFCD00012871 | [Molecular Weight]
139.58 | [MOL File]
623-33-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline | [Melting point ]
145-146 °C(lit.)
| [density ]
1.371 g/cm3 | [storage temp. ]
Store at RT. | [solubility ]
>1000 g/L (20 °C) | [form ]
Crystalline Powder | [pka]
pK1:7.66(＋1) (25°C) | [color ]
White | [Odor]
Odorless | [PH]
2.9 (10g/l, H2O, 20℃) | [Water Solubility ]
>1000 g/L (20 ºC) | [Sensitive ]
Hygroscopic | [Detection Methods]
T | [BRN ]
3594034 | [InChIKey]
TXTWXQXDMWILOF-UHFFFAOYSA-N | [CAS DataBase Reference]
623-33-6(CAS DataBase Reference) | [EPA Substance Registry System]
623-33-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R41:Risk of serious damage to eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
MC0525000
| [TSCA ]
Yes | [HS Code ]
29224995 |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline | [Uses]
As a Glycine (G615990) ester, Glycine ethyl ester hydrochloride can be used as parakeratosis inhibitor and external composition for skin.
| [Synthesis]
A production method for glycine ethyl ester hydrochloride:First add dehydrated ethanol in 1# reactor, pass into anhydrous hydrogen chloride to obtain hydrochloric acid-ethanol solution; Add a certain amount of triethyl orthoformate and glycine and hydrochloric acid-ethanol solution in 2# reactor, in the Reaction under action; after the reaction is complete, distill and recover ethanol and ethyl formate; then add alcohol-ether mixture, wash, filter, concentrate, recrystallize, and vacuum dry to obtain ethyl glycine hydrochloride. | [Purification Methods]
Crystallise it from absolute EtOH or EtOH/Et2O. [Marvel Org Synth Coll Vol II 310 1943, Beilstein 4 II 780, 4 III 3 75.] |
|
|