| Identification | More | [Name]
Sodium carbonate decahydrate | [CAS]
6132-02-1 | [Synonyms]
NATRII CARBONAS DECAHYDRICUS
SAL SODA
SODA DECAHYDRATE
SODIUM CARBONATE 10H2O
SODIUM CARBONATE-10-HYDRATE
SODIUM CARBONATE DECAHYDRATE
SODIUM CARBONATE HYDRATE
Carbonicacid,disodiumsalt,decahydrate
Salsode
Nevie
Sodium carbonate crystals
SODIUM CARBONATE-10-HYDRATE R. G., REAG. ISO, REAG. PH. EUR.
SODIUM CARBONATE DECAHYDRATE, 99.999%
SODIUM CARBONATE DECAHYDRATE PH EUR
SODIUM CARBONATE-10-HYDRATE EXTRA PURE,DAB, PH. EUR., B.
SodiumCarbonate,DecahydrateA.R.
SodiumCarbonate98%
Sodium carbonate decahydrate, 99.5+%
SODIUM CARBONATE H2O
Sodium carbonate decahydrate, 99+% | [EINECS(EC#)]
207-838-8 | [Molecular Formula]
CH20Na2O13 | [MDL Number]
MFCD00149178 | [Molecular Weight]
286.14 | [MOL File]
6132-02-1.mol |
| Chemical Properties | Back Directory | [Appearance]
white small crystals | [Melting point ]
34 °C
| [density ]
1.46
| [storage temp. ]
Store at +15°C to +25°C. | [solubility ]
H2O: 0.5 M at 20 °C, clear, colorless
| [form ]
Small Crystals | [color ]
White | [Specific Gravity]
1.46 | [PH]
11-12 (50g/l, H2O, 25℃) | [Water Solubility ]
210 g/L (20 ºC) | [Sensitive ]
Air Sensitive | [Merck ]
14,8596 | [Uses]
Washing textiles, bleaching linen and cotton,
general cleanser.
| [CAS DataBase Reference]
6132-02-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36:Irritating to the eyes. | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
3262 | [WGK Germany ]
1
| [TSCA ]
Yes | [PackingGroup ]
III | [HS Code ]
28362000 | [Toxicity]
LD50 orally in Rabbit: 4090 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
Sodium carbonate is a white, almost white, or colorless inorganic
salt, produced as crystalline powder or granules. It is hygroscopic
and odorless with an alkaline taste. | [Chemical Properties]
white small crystals | [Definition]
ChEBI: Sodium carbonate decahydrate is an organooxygen compound. | [Production Methods]
Sodium carbonate is produced by the ammonia-soda process, also
known as the Solvay process. | [Pharmaceutical Applications]
Sodium carbonate is used as an alkalizing agent in injectable,
ophthalmic, oral, and rectal formulations.
In effervescent tablets or granules, sodium carbonate is used in
combination with an acid, typically citric acid or tartaric acid.
When the tablets or granules come into contact with water, an acid–
base reaction occurs in which carbon dioxide gas is produced and
the product disintegrates. Raw materials with low moisture
contents are required to prevent the early triggering of the
effervescent reaction.
As an alkalizing agent, concentrations of sodium carbonate
between 2% and 5% w/w are used in compressed tablet
formulations. As an effervescent agent, concentrations of
sodium carbonate up to 10% w/w can be used.
Therapeutically, sodium carbonate is also used as an oral
antacid. | [Safety]
Sodium carbonate is used in injectable, oral, and rectal pharmaceutical
formulations. The pure form of sodium carbonate is mildly
toxic by ingestion, moderately toxic by inhalation and SC routes,
and very toxic by the IP route. It is irritating to the skin and eyes.
Dust and vapors of sodium carbonate may irritate mucous
membranes, causing coughing and shortness of breath. It also has
experimental reproductive effects.
Sodium carbonate can migrate to food from packaging
materials. When used as an excipient or antacid, sodium carbonate
is generally regarded as a nontoxic and nonirritating material.
LD50 (mouse, IP): 0.12 g/kg
LD50 (mouse, SC): 2.21 g/kg
LD50 (rat, oral): 4.09 g/kg | [storage]
Sodium carbonate converts to the monohydrate form when in
contact with water and produces heat. It begins to lose carbon
dioxide at temperatures above 400℃ and decomposes before
boiling. Store in airtight containers. | [Incompatibilities]
Sodium carbonate decomposes when in contact with acids in the
presence of water to produce carbon dioxide and effervescence. It
may react violently with aluminum, phosphorous pentoxide,
sulfuric acid, fluorine, and lithium. | [Regulatory Status]
GRAS listed. Accepted for use as a food additive in Europe.
Included in the FDA Inactive Ingredients Database (injections;
ophthalmic solution; oral capsules and tablets; rectal suspensions).
Included in the Canadian List of Acceptable Non-medicinal
Ingredients. Included in parenteral (powder for solution for
injection) and nonparenteral medicines (oral effervescent tablets,
soluble tablets, granules, lozenges, chewing gums) licensed in the
UK.
USP32–NF27 allows either the anhydrous or the monohydrate
form. |
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