| Identification | More | [Name]
TYRAMINE HYDROCHLORIDE | [CAS]
59880-97-6 | [Synonyms]
2-(4-HYDROXYPHENYL)ETHYLAMINE HCL
2-(4-HYDROXYPHENYL)ETHYLAMINE HYDROCHLORIDE
2-(4-HYDROXYPHENYL)ETHYLAMMONIUM CHLORIDE
4-(2-AMINOETHYL)PHENOL HYDROCHLORIDE
4-HYDROXYPHENETHYLAMINE HYDROCHLORIDE
4-HYDROXYPHENYLETHYLAMINE HCL
4-HYDROXYPHENYLETHYLAMINE HYDROCHLORIDE
P-(2-AMINOETHYL)PHENOL HYDROCHLORIDE
P-HYDROXYPHENETHYLAMINE HYDROCHLORIDE
TIMTEC-BB SBB003808
TYRAMINE
TYRAMINE HCL
TYRAMINE HYDROCHLORIDE
TYRAMINE MONOHYDROCHLORIDE
TYROSAMINE HCL
TYROSAMINE HYDROCHLORIDE
fMLF
fMLP (misnomer but widely used)
F-MET-LEU-PHE
TYRAMINE HCL(P) | [EINECS(EC#)]
200-462-5 | [Molecular Formula]
C8H12ClNO | [MDL Number]
MFCD00012901 | [Molecular Weight]
173.64 | [MOL File]
59880-97-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
271-274 °C(lit.) | [Boiling point ]
269 °C | [density ]
1.198±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMF: 50 mg/mL, clear, colorless
| [form ]
White to off-white lyophilized solid | [pka]
3.50±0.10(Predicted) | [color ]
White to Almost white | [BRN ]
2315783 | [Sequence]
N-Formyl-Met-Leu-Phe-OH | [CAS DataBase Reference]
59880-97-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S22:Do not breathe dust . | [WGK Germany ]
3
| [RTECS ]
SJ6050000
| [F ]
3-10 | [HS Code ]
2930.90.9250 |
| Hazard Information | Back Directory | [Uses]
N-Formyl-Met-Leu-Phe has been used for:
- creating gradients in Zigmond chamber chemotaxis assay performed on neutrophils
- use in neutrophil chemotaix assay and
- determination of the involvement of MAPK-activating protein kinase-2 (MAPKAPK-2) and/or p38, in the signaling pathway of human polymorphonuclear leukocytes (PMNs) stimulated by N-Formyl-Met-Leu-Phe.
| [Uses]
Induces leucocyte chemotaxis, and activates macrophages | [Definition]
ChEBI: A tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor. | [General Description]
N-Formyl-Met-Leu-Phe is a chemotactin peptide, which functions on polymorphonuclear leukocytes (PMN), neutrophils etc. | [Biochem/physiol Actions]
Potent chemotactic peptide. Induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion. | [storage]
Desiccate at -20°C |
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