| Identification | More | [Name]
2,4,5-Trichloropyrimidine | [CAS]
5750-76-5 | [Synonyms]
2,4,5-TRICHLOROPYRIMIDINE
2,5,6-TRICHLOROPYRIMIDINE
2,4,5-TRICHLOROPYRIMIDINE, 97+%
2,4,5-Trichloropyrimidine, 99+% | [EINECS(EC#)]
628-281-0 | [Molecular Formula]
C4HCl3N2 | [MDL Number]
MFCD03788200 | [Molecular Weight]
183.42 | [MOL File]
5750-76-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless to pale yellow liquid | [Boiling point ]
84°C 1mm | [density ]
1.6001 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.574(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [form ]
clear liquid | [pka]
-4.26±0.29(Predicted) | [color ]
Colorless to Light orange to Yellow | [Water Solubility ]
Not miscible or difficult to mix in water. | [BRN ]
4449 | [InChI]
InChI=1S/C4HCl3N2/c5-2-1-8-4(7)9-3(2)6/h1H | [InChIKey]
GIKMWFAAEIACRF-UHFFFAOYSA-N | [SMILES]
C1(Cl)=NC=C(Cl)C(Cl)=N1 | [CAS DataBase Reference]
5750-76-5(CAS DataBase Reference) | [Storage Precautions]
Store under nitrogen |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
3267 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29335900 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless to pale yellow liquid | [Uses]
2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. Also used in the synthesis of EGFR inhibitors. |
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