| Identification | More | [Name]
Eperisone hydrochloride | [CAS]
56839-43-1 | [Synonyms]
(4'-ethyl-2-methyl-3-piperidino)propiophenone hydrochloride
EPERISONE HCL
EPERISONE HYDROCHLORIDE
1-(4-ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanonhydrochloride
4’-ethyl-2-methyl-3-piperidino-propiophenonhydrochloride
e0646
e-646
empp
mional
myonal
Eperison hcl
Eperison Hydrochloride
EPERISON HYDROCHLORIDE,JP14
Eperizone hydrochloride
1-Propanone, 1-(4-ethylphenyl)-2-methyl-3-(1-piperidinyl)-, hydrochloride
Akitonal
Atines | [EINECS(EC#)]
1308068-626-2 | [Molecular Formula]
C17H26ClNO | [MDL Number]
MFCD00941459 | [Molecular Weight]
295.85 | [MOL File]
56839-43-1.mol |
| Hazard Information | Back Directory | [Description]
Eperisone hydrochloride is a centrally acting muscle relaxant useful in the
management of various spastic conditions including cervical spondylosis and
cerebral palsy. It is structurally related to tolperisone. | [Chemical Properties]
White Solid | [Originator]
Eisai (Japan) | [Uses]
A spasmolytic agent related structurally to Tolperisone (T535475). Muscle relaxant (skeletal). | [Uses]
Used as antispasmodic | [Definition]
ChEBI: Eperisone hydrochloride is an aromatic ketone. | [Manufacturing Process]
To 60 ml of isopropanol, there are introduced 120 g of 4-ethyl-propiophenone,
28.8g of p-formaldehyde and 107 g of piperidine hydrochloride, and the
resulting mixture is heated to reflux on an oil bath with stirring. The heating is
continued, and when the reaction mixture solidifies, the state being a sign of
completion of the reaction, there are added 500 ml of acetone thereinto. The
solidified mass is pulverized by crush, recovered by filtration and washed with
acetone. 144 g of the crude dry crystalline substance is thus obtained, which
is the hydrochloride of the purposed product. The hydrochloride is
recrystallized from isopropanol, and there are obtained the crystalline needles
having the melting point of 170°C to 172°C. | [Brand name]
MYONAL | [Therapeutic Function]
Muscle relaxant |
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