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ChemicalBook--->CAS DataBase List--->566-19-8

566-19-8

566-19-8 Structure

566-19-8 Structure
IdentificationMore
[Name]

7-Keto-dehydroepiandrosterone
[CAS]

566-19-8
[Synonyms]

5-ANDROSTEN-3-BETA-OL-7,17-DIONE
5-androstene-3b-ol-7,17-dione
7-hydroxydehydroepiandrosterone
7-KETO-DEHYDROEPIANDROSTERONE
7-KETO DHEA
DEHYDROEPIANDROSTERONE, 7-KETO
7-Oxo-dehydroepiandrosterone
androst-5-ene-7,17-dione,3beta-hydroxy
3-hydroxyandrost-5-ene-7,17-dione
7-KETO DHEA/7-KETO-DEHYDROEPIANDROSTERONE
7-KETO DHEA, HPLC 98%
7-KETODEHYDROEPIANDROSTERONE (3β-HYDROXYANDROST-5-ENE-7,17-DIONE) 7-KETODHEA
4-Androsten-3β-ol-7,17-dione-4,4,6,8,16,16-D6
[EINECS(EC#)]

1592732-453-0
[Molecular Formula]

C19H26O3
[MDL Number]

MFCD00198500
[Molecular Weight]

302.41
[MOL File]

566-19-8.mol
Chemical PropertiesBack Directory
[Melting point ]

245-248 °C
[Boiling point ]

477.1±45.0 °C(Predicted)
[density ]

1.19±0.1 g/cm3(Predicted)
[solubility ]

DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml; Ethanol: 10 mg/ml
[form ]

A crystalline solid
[pka]

14.67±0.60(Predicted)
[InChI]

InChI=1/C19H26O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h10,12-14,17,20H,3-9H2,1-2H3/t12-,13-,14-,17-,18-,19-/s3
[InChIKey]

KPRGOTLNGIBVFL-YQJRJXGQNA-N
[SMILES]

C[C@]12CC[C@H](O)CC1=CC(=O)[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,11,13,19,23,r|
[CAS DataBase Reference]

566-19-8(CAS DataBase Reference)
Questions And AnswerBack Directory
[Regulation]

The FDA has proposed that 7-Keto-DHEA be included among substances banned from use in compounded drugs.
Hazard InformationBack Directory
[Uses]

7-Keto Dehydro Epiandrosterone-d6 is the isotope labelled analog of 7-Keto Dehydro Epiandrosterone (K187700); a metabolite of Dehydroepiandrosterone (DHEA) (D229585) which is the major secretory steroidal product of the adrenal gland.
[Definition]

ChEBI: 7-ketodehydroepiandrosterone is a 3beta-hydroxy-Delta(5)-steroid that is dehydroepiandrosterone carrying an additional oxo group at position 7. It has a role as a human blood serum metabolite, a nutraceutical and a prohormone. It is a 17-oxo steroid, a 3beta-hydroxy-Delta(5)-steroid, an androstanoid and a 7-oxo steroid. It is functionally related to a dehydroepiandrosterone.
[Physiological effects]

In the past ten years, a large number of studies have shown that 7-keto dehydroepiandrosterone has stronger physiological activity than DHEA, especially in anti-aging, enhancing immunity, improving memory, enhancing brain function, preventing Alzheimer’s and diabetes , It has a strong effect on reducing the risk of heart disease, losing weight, increasing bone density and muscle vitality.
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