| Identification | Back Directory | [Name]
HEXOBARBITAL | [CAS]
56-29-1 | [Synonyms]
EVIPAL
Dorico
Evipan
Toleran
Hexenal
Citodon
Citopan
Cyclonal
Narcosan
Sombulex
Cyclopan
Enhexymal
Somnalert
Barbidorm
Noctivane
Sombucaps
Methexenyl
Cyclohexemal
Esobarbitale
HEXOBARBITAL
Hexabarbital
Hexobarbitone
hexanastaboral
Hexanastab oral
Methylhexabital
Methylhexabarbital
hexenal(barbiturate)
Hexenal (barbiturate)
LABOTEST-BB LT00244803
component of Percobarb
Hexobarbital solution
Hexobarbital CIII (500 mg)
Hexobarbital CIII (1307003)
Hexobarbital Solution, 100ppm
hexobarbital methanol solution
hexobarbital--deascheduleiiiitem
Hexobarbital (base and/or unspecified salts)
1,5-dimethyl-5-(1-cyclohexenyl)barbituricacid
5-[1-CYCLOHEXENYL]-1,5-DIMETHYLBARBITURIC ACID
1,5-Dimethyl-5-(1-cyclohexenyl)barbituric acid
5-(Cyclohexen-1-yl)-1,5-dimethylbarbitursaeure
n-methyl-5-cyclohexenyl-5-methylbarbituricacid
5-(cyclohex-1-enyl)-1,5-dimethylbarbituric acid
N-Methyl-5-cyclohexenyl-5-methylbarbituric acid
5-(Cyclohexen-1-yl)-1,5-dimethylbarbituric acid
5-(1-cyclohexen-1-yl)-1,5-dimethyl-barbituricaci
5-(1-cyclohexen-1-yl)-1,5-dimethylbarbituricacid
5-(1-Cyclohexene-1-yl)-1,5-dimethylbarbituricacid
5-(1-Cyclohexen-1-yl)-1,5-dimethylbarbituric acid
5-(1-cyclohexenyl-1)-1-methyl-5-methylbarbituricacid
Barbituric acid, 5-(1-cyclohexen-1-yl)-1,5-dimethyl-
5-(1-Cyclohexenyl-1)-1-methyl-5-methylbarbituric acid
5-(1-Cyclohexenyl)-1,5-dimethylbarbituric acid, Evipal
5-cyclohexen-1-yl-1,5-dimethyl-1,3-diazinane-2,4,6-trione
5-(delta-1,2-cyclohexenyl)-5-methyl-N-methyl-barbitursaeure
6(1h,3h,5h)-pyrimidinetrione,5-(1-cyclohexen-1-yl)-1,5-dimethyl-4
5-(1-Cyclohexen-1-yl)-1,5-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-cyclohexen-1-yl)-1,5-dimethyl- | [EINECS(EC#)]
200-264-9 | [Molecular Formula]
C12H16N2O3 | [MDL Number]
MFCD00057562 | [MOL File]
56-29-1.mol | [Molecular Weight]
236.27 |
| Chemical Properties | Back Directory | [Appearance]
White crystals. | [Melting point ]
145-147° | [Boiling point ]
378.73°C (rough estimate) | [density ]
1.1623 (rough estimate) | [refractive index ]
1.5460 (estimate) | [Fp ]
11 °C | [storage temp. ]
2-8°C | [pka]
7.99±0.10(Predicted) | [Water Solubility ]
434.7mg/L(25 ºC) | [Uses]
Medicine (sedative). | [EPA Substance Registry System]
Hexobarbital (56-29-1) |
| Hazard Information | Back Directory | [Chemical Properties]
White crystals. | [Definition]
ChEBI: A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups. | [Description]
Hexobarbital, 5-(cyclohexen-1-
yl)-1,5-dimethylbarbituric acid,Mr 236.26. The
acid forms colorless crystals that turn pink on exposure
to light, mp 146 ?C. A 10 % aqueous solution
of the sodium salt, Mr 258.25,
has a pH of 11.5. | [Brand name]
Cyclonal sodium;Cyclopan;Dorico soluble;Eviderm;Evipal sodium;Evipanl;Hexanal;Hexanastab oral. | [World Health Organization (WHO)]
Hexobarbital is a short-acting barbiturate. See WHO comment for
barbiturates. | [Clinical Use]
Methohexital sodium is a short-acting anesthetic
administered intravenously. It is very potent
and has the shortest duration of action
among the barbiturates used. A disturbing factor
is that rather frequently it causes hiccups directly
after injection. Patients are reported to recover
rapidly from anesthesia. Abuse can lead to addiction. | [Synthesis]
Hexobarbital sodium is prepared by condensation
of methyl(cyclohexen-1-yl)cyanoacetic
ester with dicyanodiamide to 5-(cyclohexen-
1-yl)-5-methyl-2,6-diimino-3-cyanobarbituric
acid, followed by methylation with dimethyl
sulfate and hydrolysis with 25 % sulfuric acid
. |
|
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