天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook--->CAS DataBase List--->53643-48-4

53643-48-4

53643-48-4 Structure

53643-48-4 Structure
IdentificationBack Directory
[Name]

DESACETYLVINBLASTINEAMIDE
[CAS]

53643-48-4
[Synonyms]

VDS
Fildesin
Eldesine
VINDESINE
Compound-112531
VINDESINE SULFATE(RG)
DESACETYLVINBLASTINEAMIDE
DESACETYLVINBLASTINEAMIDE USP/EP/BP
Compound 112531:NS C.245467:LY-099094:Hdisine:Fildisin
3-Carbamoyl-4-O-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine
3-(Aminocarbonyl)-4-O-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine
Vincaleukoblastine, 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)-
3-(Aminocarbonyl)-O^<4>^-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine
3-(aminocarbonyl)-o(sup4)-deacetyl-3-de(methoxycarbonyl)-vincaleukoblastin
3-(aminocarbonyl)-o(sup4)-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine
[EINECS(EC#)]

258-682-2
[Molecular Formula]

C43H55N5O7
[MDL Number]

MFCD01675265
[MOL File]

53643-48-4.mol
[Molecular Weight]

753.93
Chemical PropertiesBack Directory
[Melting point ]

230-232°
[alpha ]

D25 +39.4° (c = 1.0 in methanol)
[pka]

pKa (DMF 66%) 5.39, 7.36; (H2O) 6.04, 7.67(at 25℃)
Safety DataBack Directory
[RIDADR ]

1544
[HazardClass ]

6.1(a)
[PackingGroup ]

II
[Hazardous Substances Data]

53643-48-4(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Methanol-->Dichloromethane-->Ammonia-->Triphenylphosphine-->HYDRAZINE-->1-Butyl nitrite-->Vinblastine sulfate-->Vincristine sulfate-->VINBLASTINE
Hazard InformationBack Directory
[Originator]

Eldisine,Lilly ,France,1980
[Uses]

Antineoplastic.
[Definition]

ChEBI: Vindesine is a vinca alkaloid, a methyl ester, an organic heterotetracyclic compound, an organic heteropentacyclic compound, a tertiary alcohol, a tertiary amino compound and a primary carboxamide. It has a role as an antineoplastic agent. It is functionally related to a vincaleukoblastine.
[Manufacturing Process]

About 10 g of VLB (vincaleucoblastine or simply vinblastine) sulfate were converted by standard procedures to VLB free base. The free base, obtained as a residue after evaporation of the dried ethereal solvent, was dissolved in about 200 ml of anhydrous methanol. Anhydrous liquid ammonia (300 ml) was added, and the reaction mixture sealed and maintained at about 100°C for 60 hours. The reaction vessel was opened, and the contents removed and evaporated to dryness in vacuo. The resulting residue, containing 4-desacetyI VLB C-3 carboxamide, as shown by thin layer chromatography, were combined and the solvent evaporated therefrom in vacuo, yielding asa residue purified 4-desacetyl VLB C-3 carboxamide free base. The NMR and IR spectra of the solid free base confirmed the structure indicated. The free base showed a band in the infrared at 1,687 cm -l , characteristic of the amide function. The molecular weight of the free base determined by mass spectroscopy was 753 which is in agreement with theoretical value calculated for C 43 H 55 N 5 O 7 .
[Brand name]

Eldisine (Lilly).
[Therapeutic Function]

Antineoplastic
53643-48-4 suppliers list
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Website: www.approvedhomemanagement.com/ShowSupplierProductsList1549548/0.htm
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418671 +8618949823763 , +8618949823763
Website: www.tnjchem.com
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250 , +86-15129568250
Website: https://www.dideu.com
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471 , +1-2135480471
Website: https://www.sarms4muscle.com
Company Name: TargetMol Chemicals Inc.
Tel:
Website: www.targetmol.com/
Company Name: Chengdu Climax Biotech Co., Ltd.  
Tel: 028-83311324 1278112614
Website: www.climax-biotech.com
Company Name: Shanghai Raise Chemical Technology Co.,Ltd  
Tel: +86-021-50935922
Website: www.raise-chem.com
Company Name: Eastbang Pharmaceuticals Technology Co., Ltd.  
Tel: +86 (20) 28996708,29078958,28139708,29076128,28133708,28139728,28139738,28133718,021-31663278,021-31663578,021-60538387
Website: www.approvedhomemanagement.com/ShowSupplierProductsList13633/0.htm
Company Name: Sichuan Wei Keqi Biological Technology Co., Ltd.  
Tel: 028-81700200 18116577057
Website: http://www.weikeqi-biotech.com
Company Name: Chengdu HuaXia Chemical Reagent Co. Ltd  
Tel: 400-1166-196 13458535857
Website: http://www.hx-r.com
Company Name: Wuxi Zhongkun Biochemical Technology Co., Ltd.  
Tel: 0510-85629785 18013409632
Website: www.reading-chemicals.com
Company Name: Guangzhou Ciming Biological Technology Co., Ltd.  
Tel: 020-38082199,29065168,38082986,29878298,29866629,4000192398
Website: www.approvedhomemanagement.com/ShowSupplierProductsList16517/0.htm
Company Name: Wuhan ChemFaces Biochemical Co., Ltd.  
Tel: 18607101326 15172504745
Website: http://www.chemfaces.com
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Website: www.emmx.com
Company Name: Pharmacodia (Beijing) Co.,Ltd  
Tel: +86-400-851-9921
Website: www.pharmacodia.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 021-61312847; 18021002903
Website: http://www.shyuanye.com
Company Name: Shanghai ChengShao Biological Technology Co., Ltd.  
Tel: 021-61847300 13341622919
Website: www.approvedhomemanagement.com/ShowSupplierProductsList19850/0.htm
Company Name: Guangdong wengjiang Chemical Reagent Co., Ltd.  
Tel: 0751-2886750 13927877953
Website: http://www.wj-chem.com
Tags:53643-48-4 Related Product Information
143-67-9 57-22-7 24584-09-6 125317-39-7