| Identification | More | [Name]
L-NORADRENALINE BITARTRATE | [CAS]
51-40-1 | [Synonyms]
(-)-ARTERENOL BITARTRATE SALT
l-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol bitartrate
L-4-(A-HYDROXY-B-AMINOETHYL)CATECHOL BITARTRATE
L-ARTERENOL BITARTRATE
L-NORADRENALINE BITARTRATE
L-(-)-NOREPINEPHRINE-(+)-BITARTRATE
L-NOREPINEPHRINE BITARTRATE
NORADRENALINE
NORADRENALINE BITARTRATE
NOREPINEPHRINE BITARTRATE
R(-)-4-(2-AMINO-1-HYDROXYETHYL)-1,2-BENZENEDIOL-(+)-TARTRATE
(-)-noradrenalineacidtartrate
(-)-noradrenalinebitartratemonohydrate
(-)-noradrenalinetartrate
(-)-norepinephrinetartrate
alpha-(aminomethyl)-3,4-dihydroxy-benzylalcoho(-)-benzylalcohotartrate(1:1)
Benzylalcohol,.alpha.-(aminomethyl)-3,4-dihydroxy-,(-)-,tartrate(1:1)
Levarterenolbitartrate
l-noradrenalinetartrate
noradrenaline,tartrate(1:1) | [EINECS(EC#)]
200-095-0 | [Molecular Formula]
C12H17NO9 | [MDL Number]
MFCD00036384 | [Molecular Weight]
319.26 | [MOL File]
51-40-1.mol |
| Safety Data | Back Directory | [RIDADR ]
3249 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
LD50 ivn-rat: 210 mg/kg YACHDS 7,627,79 |
| Hazard Information | Back Directory | [Uses]
Adrenergic (vasoconstrictor). | [Brand name]
Levophed (Hospira). | [Clinical Use]
Hypotension
Cardiac arrest (sympathomimetic) | [Safety Profile]
Poison by intravenous andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx. | [Drug interactions]
Potentially hazardous interactions with other drugs
Adrenergic neurone blockers: antagonise hypotensive
effect.
Anaesthetics: increased risk of arrhythmias with
volatile general anaesthetics.
Antidepressants: tricyclics may cause hypertension
and arrhythmias; MAOIs and moclobemide may
cause hypertensive crisis.
Beta-blockers: can cause severe hypertension.
Clonidine: possibly increased risk of hypertension.
Dopaminergics: effects possibly increased by
entacapone; avoid with rasagiline.
Sympathomimetics: effects possibly enhanced by
dopexamine. | [Metabolism]
Extensively metabolised by catechol-O-methyltransferase
(COMT), and monoamine oxidase (MAO).
Up to 16% of an intravenous dose is excreted unchanged
in the urine with methylated and deaminated metabolites
in free and conjugated forms. | [storage]
Store at +4°C |
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