| Identification | More | [Name]
(R)-(-)-1-METHOXY-2-PROPANOL | [CAS]
4984-22-9 | [Synonyms]
(R)-(-)-1-METHOXY-2-PROPANOL
(R)-1-METHOXY-2-PROPANOL
(R)-2-HYDROXY-1-METHOXYPROPANE
(R)-(+)-PROPYLENE GLYCOL 1-METHYL ETHER
(R)-(-)-1-Methoxy-2-propanol, 98+%
(R)-(-)-1-METHOXY-2-PROPANOL 98%
(R)-1-METHOXY-2-PROPANOL,95+% | [EINECS(EC#)]
628-460-3 | [Molecular Formula]
C4H10O2 | [MDL Number]
MFCD01632587 | [Molecular Weight]
90.12 | [MOL File]
4984-22-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless to light yellow liqui | [Melting point ]
-97 °C
| [Boiling point ]
119-121 °C (lit.) | [density ]
0.921 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.403
| [Fp ]
33 °C
| [storage temp. ]
Flammables area | [form ]
Liquid | [pka]
14.49±0.20(Predicted) | [color ]
Clear colorless | [optical activity]
[α]20/D 22±2°, c = 10% in chloroform | [BRN ]
1718941 | [InChIKey]
ARXJGSRGQADJSQ-SCSAIBSYSA-N | [CAS DataBase Reference]
4984-22-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn | [Risk Statements ]
R10:Flammable.
R15:Contact with water liberates extremely flammable gases. | [Safety Statements ]
S24:Avoid contact with skin .
S43:In case of fire, use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add-Never use water) .
S7/8:Keep container tightly closed and dry . | [RIDADR ]
UN 3092 3/PG 3
| [WGK Germany ]
1
| [HazardClass ]
3 | [PackingGroup ]
Ⅲ | [HS Code ]
29051990 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless to light yellow liqui | [Uses]
(R)-(-)-1-Methoxy-2-propanol can be used as a reactant to prepare:
- (S)-3-(ethoxycarbonyl)-5-((1-methoxypropan-2-yl)oxy)benzoic acid, a key intermediate to synthesize phenylethyl benzamide derivatives, which can be used as glucokinase activators.
- Chiral pyrazolopyrimidinone derivatives as potential phosphodiesterase enzyme (PDE5) inhibitors.
- Aryl or alkyl ethers via etherification reaction.
| [General Description]
(R)-(-)-1-Methoxy-2-propanol is a chiral secondary alcohol. It is formed during the hydrolysis of (R)-1-methoxy-2-propyl-acetate in the presence of Candida antarctica lipase B. |
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