| Identification | More | [Name]
Ethyl propionylacetate | [CAS]
4949-44-4 | [Synonyms]
3-KETO-N-VALERIC ACID ETHYL ESTER
3-KETOVALERIC ACID ETHYL ESTER
3-OXOVALERIC ACID ETHYL ESTER
ETHYL 3-OXOPENTANOATE
ETHYL 3-OXOVALERATE
ETHYL PROPIONYLACETATE
PROPIONYLACETIC ACID ETHYL ESTER
3-oxo-pentanoicacidethylester
Ethyl 3-oxo-n-valerate
Pentanoic acid, 3-oxo-, ethyl ester
Ethylpropionylacetate,95%
Ethyl propionylacetate, 98+%
Ethyl propanoylacetate
thyl 3-ketopentanoate | [EINECS(EC#)]
225-593-5 | [Molecular Formula]
C7H12O3 | [MDL Number]
MFCD00009317 | [Molecular Weight]
144.17 | [MOL File]
4949-44-4.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless liquid | [Melting point ]
98 °C | [Boiling point ]
83-84 °C/12 mmHg (lit.) | [density ]
1.012 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.422(lit.)
| [Fp ]
172 °F
| [storage temp. ]
Refrigerator | [solubility ]
Miscible with glacial acetic acid. | [form ]
Liquid | [pka]
10.58±0.46(Predicted) | [color ]
Clear colorless to pale yellow | [Specific Gravity]
1.01 | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents. | [BRN ]
970270 | [InChIKey]
UDRCONFHWYGWFI-UHFFFAOYSA-N | [CAS DataBase Reference]
4949-44-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethyl propionylacetate(4949-44-4) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [TSCA ]
T | [HazardClass ]
IRRITANT | [HS Code ]
29183000 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
TRIPHENYLMETHYL SODIUM-->2,2-diMethyl-5-propanoyl-1,3-dioxane-4,6-dione-->Pentanoic acid, 2-diazo-3-hydroxy-, ethyl ester-->2-Oxazolidinone, 3-(1-oxopropyl)--->Carbon tetrachloride-->Iodomethane-->Ethyl acetate-->3-Propionylthiazolidine-2-thione-->Propionyl chloride-->Pentanoic acid,3-hydroxy-, ethyl ester-->3,5-Dimethyl-1-(1-Oxopropyl)-1H-Pyrazole-->4-Pentenoic acid, 3-hydroxy-, ethyl ester-->2,2-Dimethyl-1,3-dioxane-4,6-dione-->Diethyl malonate | [Preparation Products]
Etodolac-->ETHYL 4-FLUORO-3-OXOPENTANOATE |
| Hazard Information | Back Directory | [Chemical Properties]
colourless liquid | [Uses]
An intermediate of Rosuvastatin. | [Synthesis Reference(s)]
Synthesis, p. 829, 1978 DOI: 10.1055/s-1978-24903 | [General Description]
Ethyl propionylacetate reacts with tropolone p-toluenesulfonate in the presence of sodium ethoxide to give 3-propionyl-2H-cyclohepta[b]furan-2-one. |
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