Identification | More | [Name]
5ALPHA-CHOLESTANE | [CAS]
481-21-0 | [Synonyms]
(5A)-CHOLESTANE 5ALPHA-CHOLESTANE ALPHA, ALPHA, ALPHA 20R-CHOLESTANE CHOLESTANE CHOLESTANE, (5A-)- CHOLESTANE(5-ALPHA) 10,13-Dimethyl-17-(1',5'-dimethylhexyl)-hexadecahydrocyclopenta(a)phenanthrene 28,29,30-Trinorlanostane 5A-Cholestane, TMS 5-α-cholestane alpha-Cholestane 5-ALPHA-CHOLESTANE 1X1ML CHLOROFORM 10MG /ML (5ALPHA-)-CHLOLESTANE 5alpha-Cholestane, 98+% (13β)-5α-Cholestane | [EINECS(EC#)]
207-562-8 | [Molecular Formula]
C27H48 | [MDL Number]
MFCD00066412 | [Molecular Weight]
372.67 | [MOL File]
481-21-0.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. R38:Irritating to the skin. R40:Limited evidence of a carcinogenic effect. R48/20/22:Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . S36/37:Wear suitable protective clothing and gloves . | [RIDADR ]
UN 1888 6.1/PG 3 | [WGK Germany ]
3
| [HS Code ]
29021990 |
Hazard Information | Back Directory | [Description]
5α-Cholestane is a sterol that has been found in dust samples from urban and rural paved and agricultural and public unpaved roads.1 It has been used as an internal standard for the quantification of phytosterols by HPLC-MS/MS and fecal sterols by GC-FID and GC-MS.2,3 | [Chemical Properties]
WHITE CRYSTALLINE POWDER | [Uses]
5α-Cholestane was used as standard in cholesterol analysis by GC and HPLC. | [Uses]
α-Cholestane is the trans-decalin homolog of Coprostane. | [Definition]
ChEBI: The 5alpha-stereoisomer of cholestane. | [Biochem/physiol Actions]
5α-Cholestane is a sterol produced endogenously from cholesterol and has been isolated from human feces. It is derived from cholesterol by the action of intestinal microorganisms. Derivatives of 5α-cholestane in plants are called Brassinosteroids that selectively activate the PPI3K/Akt pathway. | [Purification Methods]
Crystallise 5-cholestane from Et2O/EtOH or EtOAc. [Ruzicka et al. Helv Chim Acta 16 327 1933, Beilstein 5 III 1132, 5 IV 1227.] |
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