| Identification | Back Directory | [Name]
N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine | [CAS]
474-74-8 | [Synonyms]
Lithocholylglycine
Glycolithocholic-d4 Acid
Ursodeoxycholic Impurity 13
Urosodeoxycholic Acid Impurity 13
Lithocholic acid glycine conjugate
Glycolithocholic Acid MaxSpec? Standard
N-[(3α,5β)-3-Ηydroxy-24-oxocholan-24-yl]glycine
Glycine, N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-
Glycine, N-[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]-
N-[(3a,5b)-3-hydroxy-24-oxocholan-24-yl]-(9CI) Glycine | [EINECS(EC#)]
207-494-9 | [Molecular Formula]
C26H43NO4 | [MDL Number]
MFCD00067140 | [MOL File]
474-74-8.mol | [Molecular Weight]
433.63 |
| Chemical Properties | Back Directory | [Melting point ]
212-214 °C | [Boiling point ]
546.95°C (rough estimate) | [density ]
1.0738 (rough estimate) | [refractive index ]
1.6000 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly, Heated), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
3.58±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
Glycolithocholic acid is a glycine-conjugated form of the secondary bile acid lithocholic acid . It is increased in the liver of mice fed a diet supplemented with ursodeoxycholic acid . Glycolithocholic acid levels are decreased in the plasma following subcutaneous administration of PEG-obestatin(Cys10, Cys13), a modified peptide hormone, in lean or diet-induced obese mice. Serum glycolithocholic acid levels increase with age in children. | [Uses]
A metabolite in human hepatic bile. | [Uses]
A metabolite in human hepatic bile. A lithocholic acid analog that inhibit sialyltransferase. | [Definition]
ChEBI: The glycine conjugate of lithocholic acid. |
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