| Identification | More | [Name]
2-Bromopyrimidine | [CAS]
4595-60-2 | [Synonyms]
2-BROMOPYRIMIDINE
PYRIMIDINE, 2-BROMO-
2-bromo-pyrimidin
Pyrimidine, 2-bromo-(7CI,8CI,9CI)
2-Bromopyrimidine,98+%
2-Bromopyrimide | [EINECS(EC#)]
224-993-7 | [Molecular Formula]
C4H3BrN2 | [MDL Number]
MFCD00014601 | [Molecular Weight]
158.98 | [MOL File]
4595-60-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [TSCA ]
Yes | [HazardClass ]
IRRITANT | [HS Code ]
29335900 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
2-Chloropyrimidine-->2-Aminopyrimidine | [Preparation Products]
2-Methylpyrimidine-->2,2'-BIPYRIMIDINE-->PYRIMIDIN-2-YLBORONIC ACID-->2,4-DIBROMOPYRIMIDINE-->3-PyriMidin-2-yl-1H-indole, 98+% C12H9N3, MW: 195.23-->Pyrimidine, 2,2-(1,4-phenylene)bis- (9CI)-->Pyrimidine, 2-(ethylthio)- (7CI,8CI,9CI)-->DiMethyl 2-(2-PyriMidyl)Malonate-->Pyrimidine, 2-ethenyl- (9CI)-->3-fluoro-2-(pyrimidin-2-yl)benzonitrile |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white crystalline powder | [Uses]
2-Bromopyrimidine is used in the preparation of 2,7-bis(2-pyrimidyl)-9,9-dihexylfluorene by cross-coupling with 9,9-dihexylfluorene-2,7-diboronic acid. It undergoes microwave-assisted aminocarbonylation at C-2 with palladium and molybdenum hexacarbonyl. | [Preparation]
The recent synthesis of 2-bromopyrimidine by diazotization of 2-aminopyrimidine in hydrobromic acid has furnished a convenient starting material for other 2-substituted pyrimidines. | [General Description]
2-Bromopyrimidine undergoes microwave-assisited aminocarbonylation at C-2 with palladium and Mo(CO)6. |
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