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ChemicalBook--->CAS DataBase List--->4027-57-0

4027-57-0

4027-57-0 Structure

4027-57-0 Structure
IdentificationMore
[Name]

Ethyl 3-methyl-1H-pyrazole-5-carboxylate
[CAS]

4027-57-0
[Synonyms]

5-METHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
AKOS PAO-0427
BUTTPARK 29\06-79
ETHYL 3-METHYL-1H-PYRAZOLE-5-CARBOXYLATE
ETHYL 3-METHYL-5-PYRAZOLECARBOXYLATE
ETHYL 3-METHYLPYRAZOLE-5-CARBOXYLATE
ETHYL 5-METHYL-2H-PYRAZOLE-3-CARBOXYLATE
1H-Pyrazole-3-carboxylic acid, 5-methyl-, ethyl ester
3-Methylpyrazole-5-carboxylic acid ethyl ester
Ethyl 3-methyl-1h-pyrazole-5-carboxylate, 95+%
Ethyl 3-methylpyrazole-5-carboxylate ,98%
5-Methyl-1H-pyrazole-3-carboxylic acid ethyl ester
[EINECS(EC#)]

223-702-0
[Molecular Formula]

C7H10N2O2
[MDL Number]

MFCD00052514
[Molecular Weight]

154.17
[MOL File]

4027-57-0.mol
Chemical PropertiesBack Directory
[Melting point ]

80-84 °C (lit.)
[Boiling point ]

299.1±20.0 °C(Predicted)
[density ]

1.171±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[pka]

11.60±0.10(Predicted)
[Detection Methods]

HPLC
[BRN ]

4192
[InChIKey]

BOTXQJAHRCGJEG-UHFFFAOYSA-N
[CAS DataBase Reference]

4027-57-0(CAS DataBase Reference)
[NIST Chemistry Reference]

3(5)-methyl-5(3)-ethoxycarbonylpyrazole(4027-57-0)
[Storage Precautions]

Moisture sensitive
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
[WGK Germany ]

3
[Hazard Note ]

Irritant
[HazardClass ]

IRRITANT
[HS Code ]

29331990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethanol-->Sodium-->Acetone-->Hydrazinium hydroxide solution-->Diethyl oxalate-->Hydrazine monohydrochloride
[Preparation Products]

4-CHLORO-2,5-DIMETHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID-->5-Methyl-1H-pyrazole-3-carboxylic acid-->1,5-DIMETHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID-->(E)-N-(2,6-dichlorobenzylidene)-3-methyl-1H-pyrazole-5-carbohydrazide-->5-Methyl-3-methanol-1H-pyrazol [1R-(1,2,5)]-->ethyl 3-Methyl-1-propyl-1H-pyrazole-5-carboxylate-->3-Methyl-1-propyl-1H-pyrazole-5-carboxylic acid
Hazard InformationBack Directory
[Chemical Properties]

White to yellow solid
[Uses]

Ethyl 3-Methyl-5-pyrazolecarboxylate is a useful synthetic intermediate. It is used to prepare tetrahydroisoquinoline amide substituted Ph pyrazoles as selective Bcl-2 inhibitors. It is also studies as a hypolipidemic agent.
[General Description]

Ethyl 3-methylpyrazole-5-carboxylate can be prepared by reacting ethyl acetylpyruvate and hydrazine.
Spectrum DetailBack Directory
[Spectrum Detail]

Ethyl 3-methyl-1H-pyrazole-5-carboxylate(4027-57-0)MS
Ethyl 3-methyl-1H-pyrazole-5-carboxylate(4027-57-0)IR1
Ethyl 3-methyl-1H-pyrazole-5-carboxylate(4027-57-0)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

ethyl 3-methyl-1H-pyrazole-5-carboxylate(4027-57-0)
[Alfa Aesar]

Ethyl 3-methyl-1H-pyrazole-5-carboxylate, 97%(4027-57-0)
[Sigma Aldrich]

4027-57-0(sigmaaldrich)
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