Identification | More | [Name]
N-Hydroxyethylphthalimide | [CAS]
3891-07-4 | [Synonyms]
2-(2-hydroxyethyl)-1h-isoindole-1,3(2h)-dione 2-PHTHALIMIDOETHANOL AKOS BBS-00004429 N-(2-HYDROXYETHYL)PHTHALIMIDE N-(BETA-HYDROXYETHYL)PHTHALIMIDE N-HYDROXYETHYLPHTHALIMIDE TIMTEC-BB SBB003638 1H-Isoindole-1,3(2H)-dione, 2-(2-hydroxyethyl)- 2-(2-hydroxyethyl)-1h-isoindole-3(2h)-dione 2-Hydroxyethylphthalimide Phthalimide, N-(2-hydroxyethyl)- N-hydroethyl phthalimide N-(2-Hydroxyethyl)phthalimide, 98+% | [EINECS(EC#)]
223-434-4 | [Molecular Formula]
C10H9NO3 | [MDL Number]
MFCD00005903 | [Molecular Weight]
191.18 | [MOL File]
3891-07-4.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust . S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29251900 |
Hazard Information | Back Directory | [Chemical Properties]
white crystalline powder | [Uses]
N-(2-Hydroxyethyl)phthalimide is used as a reagent to synthesize (-)-R-rolipram is a phosphodiesterase 4 inhibitor that is used to treat depression. N-(2-Hydroxyethyl)phthalimide is also used as a reagent to synthesize FR252921, a compound that acts as an immunosuppressant. Amlodipine Impurity 6 | [Synthesis Reference(s)]
Organic Syntheses, Coll. Vol. 4, p. 106, 1963 The Journal of Organic Chemistry, 24, p. 1122, 1959 DOI: 10.1021/jo01090a601 | [General Description]
N-(2-Hydroxyethyl)phthalimide is the precursor for chloromethyl ethers used in the synthesis of purine acyclic nucleosides. |
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