| Identification | More | [Name]
3-Fluoropyridine | [CAS]
372-47-4 | [Synonyms]
3-FLUOROPYRIDINE
Pyridine, 3-fluoro-
3-Fluoroypyridine
3-FLUOROPYRIDINE 98% (GC)
3-Fluoropyridine,98%
3-Fluoropyridine 98% | [EINECS(EC#)]
206-755-4 | [Molecular Formula]
C5H4FN | [MDL Number]
MFCD00006374 | [Molecular Weight]
97.09 | [MOL File]
372-47-4.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR YELLOW LIQUID | [Melting point ]
251-254°C (dec.) | [Boiling point ]
107-108 °C (lit.) | [density ]
1.13 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.472(lit.)
| [Fp ]
56 °F
| [storage temp. ]
Flammables area | [form ]
Liquid | [pka]
pK1:2.97(＋1) (25°C) | [color ]
Clear yellow | [Specific Gravity]
1.130 | [BRN ]
105702 | [InChIKey]
CELKOWQJPVJKIL-UHFFFAOYSA-N | [CAS DataBase Reference]
372-47-4(CAS DataBase Reference) | [NIST Chemistry Reference]
3-F-pyridine(372-47-4) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xi,Xn | [Risk Statements ]
R11:Highly Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S33:Take precautionary measures against static discharges .
S7/9:Keep container tightly closed and in a well-ventilated place . | [RIDADR ]
UN 1993 3/PG 2
| [WGK Germany ]
3
| [Hazard Note ]
Flammable/Irritant | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR YELLOW LIQUID | [Uses]
3-Fluoropyridine was used in the synthesis of 3-halopyridin-4-yl-boronic acids and esters. | [Preparation]
A combination of CsF and HF provides a very reactive fluoride source and has shown faint promise with 3-chloropyridine giving 3-fluoropyridine in a very low yield.
 | [General Description]
3-Fluoropyridine is oxidized to corresponding N-oxides, which on treatment with hot acetic anhydride and hydrolysis yields 3-halo-2-pyridones. Microwave spectrum of 3-fluoropyridine has been investigated in the frequency range of 8-18GHz at dry ice temperature. Deprotonation of 3-fluoropyridine with Bu3MgLi in THF at -10°C has been studied. |
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