| Identification | More | [Name]
(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE | [CAS]
36394-75-9 | [Synonyms]
AP-CL
O-ACETYL-L-LACTYL CHLORIDE
(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE
(S)-2-ACETOXYPROPIONYL CHLORIDE
S-ACETOXYPROPIONYL CHLORIDE
(S)-(-)-O-ACETYLLACTOYL CHLORIDE
2-Acetoxy propionyl chloride
L-(-)-2-ACETOXYPROPIONYL CHLORIDE
(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE 97+%
O-Acetyl-L-lactyl chloride, AP-Cl
(S)-2-Acetoxypropionic acid chloride
[(2S)-2-Acetoxypropionyl] chloride
Acetic acid (S)-1-(chlorocarbonyl)ethyl ester
Acetic acid (S)-1-methyl-2-oxo-2-chloroethyl ester
Mosandl reagent | [EINECS(EC#)]
420-610-4 | [Molecular Formula]
C5H7ClO3 | [MDL Number]
MFCD00145252 | [Molecular Weight]
150.56 | [MOL File]
36394-75-9.mol |
| Chemical Properties | Back Directory | [alpha ]
-31o (C=4 IN CHLOROFORM) | [Boiling point ]
50 °C5 mm Hg(lit.)
| [density ]
1.189 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.423(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
Chloroform (Sparingly) | [form ]
clear liquid | [color ]
Colorless to Light yellow | [Specific Gravity]
1.19 | [optical activity]
[α]20/D 31°, c = 4 in chloroform | [BRN ]
1722943 | [Stability:]
Hygroscopic, Moisture sensitive | [CAS DataBase Reference]
36394-75-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
3
| [F ]
10-21 | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
2918199890 |
| Hazard Information | Back Directory | [Uses]
Frequently used chiral building block. Also used to resolve a bicyclic α-hydroxylactone and to prepare chiral phosphonates used in an enantiomeric excess assay of unprotected amino acids. Useful chiral derivatizing agent. | [Purification Methods]
It is moisture sensitive and is hydrolysed to the corresponding acid. Check the IR spectrum. If the OH band above 3000cm -1 is too large and broad then the mixture should be refluxed with pure acetyl chloride for 1hour, evaporated and distilled under reduced pressure. [Julia & Sans J Chromatographic Sci 17 651 1979, Dolittle & Heath J Org Chem 49 5041 1984, Beilstein 3 II 189.] |
|
|