Identification | More | [Name]
(R)-(-)-2-Amino-1-propanol | [CAS]
35320-23-1 | [Synonyms]
(+/-)-2-AMINO-1-PROPANOL 2-AMINO PROPANOL (2R)-2-AMINO-1-PROPANOL D-2-AMINO-PROPANOL D-(-)-ALANINOL D-ALANINOL D-ALAOH DL-2-AMINO-1-PROPANOL DL-2-AMINO PROPANOL DL-2-AMINOPROPYL-ALCOHOL DL-ALANILOL DL-ALANINOL H-D-ALANINOL H-D-ALA-OL H-DL-ALA-OL (R)-(-)-2-AMINO-1-PROPANOL (R)-2-AMINO-1-PROPANOL (R)-(-)-2-AMINOPROPANOL (R)-1-Aminopropan-2-ol D-amine propionic acid | [EINECS(EC#)]
228-207-3 | [Molecular Formula]
C3H9NO | [MDL Number]
MFCD00008085 | [Molecular Weight]
75.11 | [MOL File]
35320-23-1.mol |
Chemical Properties | Back Directory | [Appearance]
Colorless to light yellow liqui | [Melting point ]
8 °C
| [alpha ]
-17 º (c=neat) | [Boiling point ]
173-176 °C(lit.)
| [density ]
0.965 | [refractive index ]
n20/D 1.450(lit.)
| [Fp ]
183 °F
| [storage temp. ]
2-8°C
| [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Oily Liquid | [pka]
12.88±0.10(Predicted) | [color ]
Clear colorless to light yellow | [Specific Gravity]
0.965 | [optical activity]
[α]19/D 18°, neat | [Water Solubility ]
SOLUBLE | [Sensitive ]
Hygroscopic | [Detection Methods]
GC | [BRN ]
1718866 | [CAS DataBase Reference]
35320-23-1(CAS DataBase Reference) | [NIST Chemistry Reference]
(R)-(-)-2-Amino-1-propanol(35320-23-1) | [Storage Precautions]
Store under nitrogen;Air sensitive |
Safety Data | Back Directory | [Hazard Codes ]
C,Xi | [Risk Statements ]
R34:Causes burns. R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . S36:Wear suitable protective clothing . | [RIDADR ]
UN 2735 8/PG 2
| [WGK Germany ]
3
| [F ]
10-23 | [Hazard Note ]
Corrosive/Hygroscopic | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29221990 |
Hazard Information | Back Directory | [Chemical Properties]
Colorless to light yellow liqui | [Uses]
(R)-(-)-2-Amino-1-propanol has been used as a derivatizing agent for gossypol during the analysis of gossypol enantiomers in cottonseed by high-performance liquid chromatography. | [Application]
R)-(-)-2-Amino-1-propanol is used as a chiral intermediate for the synthesis of pharmaceutical products and agrochemicals. It acts as additives in health care products and animal feed. It is a amino alcohol
obtained by reduction of d-alanine. This compound could be converted into the corresponding nonracemic
adenine derivative (R)-9-(1-Methyl-2-hydroxyethyl)adenine through minor variations on the classic
Montgomery sequence[1].
| [General Description]
(R)-(-)-2-Amino-1-propanol is a chiral secondary amine. | [References]
[1] Jeffery A, et al. Synthesis of Acyclic Nucleoside and Nucleotide Analogues from
Amino Acids: A Convenient Approach to a PMEA±PMPA Hybrid. Tetrahedron, 2000; 56: 5077-5083. |
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