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ChemicalBook--->CAS DataBase List--->343630-41-1

343630-41-1

343630-41-1 Structure

343630-41-1 Structure
IdentificationBack Directory
[Name]

NS 3623
[CAS]

343630-41-1
[Synonyms]

NS 3623
1-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
N-[4-Bromo-2-(1H-tetrazol-5-yl-phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea
[Molecular Formula]

C15H10BrF3N6O
[MOL File]

343630-41-1.mol
[Molecular Weight]

427.18
Chemical PropertiesBack Directory
[density ]

1.759±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble to 100 mM in DMSO
[form ]

Powder
[pka]

3.95±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS06
[Signal word ]

Danger
[Hazard statements ]

H301-H413
[Precautionary statements ]

P264-P270-P273-P301+P310+P330-P405-P501
Hazard InformationBack Directory
[Uses]

NS 3623 selectively activates the human ether-a-go-go related gene (hERG) potassium channel which mediates the repolarizing cardiac current IKr. NS 3623 an IKr agonist, cause QT interval prolongation, increasing the risk of dangerous ventricular fibrillations, eventually leading to sudden cardiac death.
[storage]

Store at -20°C
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