| Identification | More | [Name]
BIS(2,2,2-TRIFLUOROETHYL) ETHER | [CAS]
333-36-8 | [Synonyms]
2,2,2-TRIFLUOROETHYL ETHER
BIS(2,2,2-TRIFLUOROETHYL) ETHER
DI(2,2,2-TRIFLUOROETHYL)ETHER
FLUROTHYL
1,1,1-Trifluoro-2-(2,2,2-trifluoroethoxy)ethane
2-(2,2,2-Trifluoroethoxy)-1,1,1-trifluoroethane
Bis(trifluoroethyl)ether
Ethane, 1,1'-oxybis[2,2,2-trifluoro-
Ether, bis(2,2,2-trifluoroethyl)
ether,bis(2,2,2-trifluoroethyl)
Fluoroethyl
Fluorothyl
Flurotyl
Hexafluorodiethyl ether
hexafluorodiethylether
HFE
Idoklon
Indiklon
Indoklon
SF6539 | [Molecular Formula]
C4H4F6O | [MDL Number]
MFCD00010604 | [Molecular Weight]
182.06 | [MOL File]
333-36-8.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless liquid | [Melting point ]
25°C | [Boiling point ]
62-63 °C (lit.) | [density ]
1.404 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.300(lit.)
| [Fp ]
35 °F
| [storage temp. ]
Flammables area | [solubility ]
DMSO : ≥ 125 mg/mL (686.59 mM) | [form ]
clear liquid | [color ]
Colorless to Almost colorless | [Specific Gravity]
1.41 | [Merck ]
4201 | [BRN ]
1811927 | [CAS DataBase Reference]
333-36-8(CAS DataBase Reference) | [EPA Substance Registry System]
HFE-356mff2 (333-36-8) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xi,T | [Risk Statements ]
R11:Highly Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 3271 3/PG 2
| [WGK Germany ]
3
| [RTECS ]
KN3675000
| [Hazard Note ]
Flammable/Toxic/Convulsant | [HazardClass ]
3.1 | [PackingGroup ]
II | [HS Code ]
29091990 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless liquid | [Originator]
Indoklon ,Ohio Medical, US ,1964 | [Uses]
5HT agonist | [Definition]
ChEBI: Flurotyl is an ether. | [Manufacturing Process]
23 parts of sodium metal were placed in 300 parts of dry dioxane in a reactor equipped with an agitator and reflux condenser. The dioxane was heated to reflux while stirring.150 parts of 2,2,2-trifluoroethanol were added very slowly in the period of about 1 hour, or until the sodium was all reacted, to form sodium 2,2,2-trifluoroethylate. 250 parts of 2,2,2-trifluoroethyl ptoluenesulfonate prepared by reacting 2,2,2-trifluoroethanol with p
Flurothyl toluenesulfonyl chloride were placed in another reactor and heated to about 160° to 185°C. The solution of sodium 2,2,2-trifluoroethylate in dioxane was added very slowly over a period of about 1? hours. Bis(2,2,2-trifluoroethyl) ether formed continuously and distilled from the reactor with the dioxane into a cooled receiving vessel. The condensed effluent from the reactor was fractionally distilled, yielding 46.5 parts of products boiling at 55° to 73°C.
The crude product was washed successively with concentrated HCl, 62% H2SO4,concentrated H2SO4 and 5% NaOH solution. It was dehydrated over a drying agent and then refractionated in a still. 20 parts of bis(2,2,2trifluoroethyl) ether were recovered (BP 62.5° to 63.5°C). | [Brand name]
Indoklon (Ohmeda). | [Therapeutic Function]
Central stimulant, Convulsant |
| Spectrum Detail | Back Directory | [Spectrum Detail]
BIS(2,2,2-TRIFLUOROETHYL) ETHER(333-36-8)MS
BIS(2,2,2-TRIFLUOROETHYL) ETHER(333-36-8)1HNMR
BIS(2,2,2-TRIFLUOROETHYL) ETHER(333-36-8)13CNMR
BIS(2,2,2-TRIFLUOROETHYL) ETHER(333-36-8)IR1
BIS(2,2,2-TRIFLUOROETHYL) ETHER(333-36-8)Raman
|
|
|