| Identification | Back Directory | [Name]
1-CYCLOHEXYLPIPERIDINE | [CAS]
3319-01-5 | [Synonyms]
CYCLOHEXYL PIPERIDINE
1-cyclohexyl-piperidin
N-Cyclohexylpiperidine
1-CYCLOHEXYLPIPERIDINE
1-Piperidinocyclohexane
Piperidine, 1-cyclohexyl-
1-Cyclohexylpiperidine > | [EINECS(EC#)]
222-016-9 | [Molecular Formula]
C11H21N | [MDL Number]
MFCD00014642 | [MOL File]
3319-01-5.mol | [Molecular Weight]
167.29 |
| Chemical Properties | Back Directory | [Melting point ]
73-74 °C(Solv: benzene (71-43-2); ligroine (8032-32-4)(1:5)) | [Boiling point ]
231-234°C | [density ]
0,914 g/cm3 | [refractive index ]
1.4856 | [Fp ]
231-234°C | [form ]
clear liquid | [pka]
10.07±0.20(Predicted) | [color ]
Colorless to Light yellow | [Water Solubility ]
Immiscible with water. | [BRN ]
105594 |
| Safety Data | Back Directory | [Risk Statements ]
36/38 | [Safety Statements ]
26-36 | [RTECS ]
TM6520000 | [HS Code ]
2933.39.9200 | [Toxicity]
mouse,LD50,intravenous,32mg/kg (32mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02603, |
| Hazard Information | Back Directory | [Uses]
1-Cyclohexylpiperidine is used in the preparation of 1-(1-phenylcyclohexyl)piperidine, which shows anticholinesterase activity and antagonistic activity to acetylcholine. It is used as a N-methyl-D-aspartate receptor (NMDAR) antagonist. Further, it is used as an anesthetic for animals. | [Definition]
ChEBI: N-cyclohexylpiperidine is a member of piperidines. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 72, p. 1597, 1950 DOI: 10.1021/ja01160a046
Tetrahedron, 52, p. 10835, 1996 DOI: 10.1016/0040-4020(96)00631-X |
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