| Identification | More | [Name]
D-Glucurone | [CAS]
32449-92-6 | [Synonyms]
D-GLUCOFURANOURONO-6,3-LACTONE
D-GLUCOFURANURONO-6,3-LACTONE
D(+)GLUCORONIC ACID GAMMA-LACTONE
D-GLUCORONIC ACID LACTONE
D-GLUCURANO-3,6-LACTONE
D-GLUCURONE
D(+)-GLUCURONIC ACID GAMMA-LACTONE
D-GLUCURONIC ACID-GAMMA-LACTONE
D-GLUCURONIC ACID LACTONE
D-GLUCURONO-1,4-LACTONE
D(+)-GLUCURONO-3,6-LACTONE
D-GLUCURONO-3,6-LACTONE
D(+)-GLUCURONO-6,3-LACTONE
D-GLUCURONO-6,3-LACTONE
D(+)-GLUCURONOLACTONE
D-GLUCURONOLACTONE
GLUCURONO-3,6-LACTONE(-D)
GLUCURONO-GAMMA-LACTONE
GLUCURONOLACTONE
b-d-anhydroglucuronate | [EINECS(EC#)]
251-053-3 | [Molecular Formula]
C6H8O6 | [MDL Number]
MFCD00135622 | [Molecular Weight]
176.12 | [MOL File]
32449-92-6.mol |
| Chemical Properties | Back Directory | [Definition]
The γ-lactone of glucuronic acid. Found in plant gums and animal connective tissues. | [Appearance]
white crystals or crystalline powder | [Melting point ]
172-175 °C (lit.) | [alpha ]
19 º (c=10, H2O) | [Boiling point ]
227.71°C (rough estimate) | [density ]
1,76 g/cm3 | [refractive index ]
18.5 ° (C=5, H2O) | [storage temp. ]
Store at RT. | [solubility ]
water: soluble25mg/mL, clear, colorless | [form ]
Crystals or Crystalline Powder | [pka]
11.96±0.60(Predicted) | [color ]
White | [Odor]
at 100.00 %. very mild mentholic | [Odor Type]
mentholic | [optical activity]
[α]24/D +18.8°, c = 8 in H2O | [Water Solubility ]
SOLUBLE | [Merck ]
14,4467 | [BRN ]
83595 | [InChIKey]
OGLCQHRZUSEXNB-IEPORWDDSA-N | [LogP]
-3.457 (est) | [CAS DataBase Reference]
32449-92-6(CAS DataBase Reference) | [EPA Substance Registry System]
32449-92-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
2
| [RTECS ]
LZ8930000
| [TSCA ]
Yes | [HS Code ]
29322980 |
| Hazard Information | Back Directory | [Chemical Properties]
white crystals or crystalline powder | [Uses]
D-Glucurone is a glucuronic acid derivative. It is used for treating canine hepatitis.
| [General Description]
D-(+)-Glucuronic acid γ-lactone (Glucourono-γ-lactone, Glucurone or Glycurone) is a carbohydrate derivative. It converted into L-ascorbic acid in animals and human body. Its molecule contains two five-membered rings. Its crystal structure has been studied. | [Purification Methods]
Dissolve the lactone or mixture of lactone and acid in H2O and concentrate on a steam bath until crystallisation begins. Cool rapidly to room temperature wih stirring. After 2hours the product is filtered off, washed with cold EtOH and dried to m 174-175o and [] D +19.8o (c 5.2, H2O). The amount of free acid can be obtained by titration of an ice-cold aqueous solution with standard alkali. It can be recrystallised from EtOH, EtOH/H2O or MeOH, and the highest recorded m is 180o. [Stacey J Chem Soc 1529 1939, Mehltretter et al. J Am Chem Soc 73 2424 1951, Beilstein 18 III/IV 3055, 18/5 V 33.] |
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