Identification | More | [Name]
(-)-Corey lactone 4-phenylbenzoate alcohol | [CAS]
31752-99-5 | [Synonyms]
(3AALPHA,4ALPHA,5BETA,6AALPHA)-(-)-HEXAHYDRO-4-(HYDROXYMETHYL)-2-OXO-2H-CYCLOPENTA[B]FURAN-5-YL 1,1'-BIPHENYL-4-CARBOXYLATE (-)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL (3aR,4S,5R,6aS)-Hexahydro-4-hydroxymethyl-5-(4-phenylbenzoyloxy)cyclopenta[b]furan-2-one, 99% (-)-COREY LACTONE 4-PHENYLBENZOATE 4-Phenylbenzoyl corey lactone (-)-COREY LACTONE 4-PHENYLBENZOATE ALCOHOL 99% (-)-Corey lactone 4-phenylbenzoate alcohol (3aalpha,4alpha,5beta,6aalpha)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1'-biphenyl-4-carboxylate (3aR,4S,5R,6aS)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1'-biphenyl-4-carboxylate (-)-Corey lactone, 4-PBP (-)-Corey lactone 5-(4-phenylbenzoate, (-)-Corey lactone, 4-phenylbenzoate alcohol, (3aα,4α,5β,6aα)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1μ-biphenyl-4-carboxylate (-)-Corey lactone 5-(4-phenylbenzoate, (3aα,4α,5β,6aα)-(-)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1μ-biphenyl-4-carboxylate (-)-Corey lactone, 4-phenylbenzoate alco-hol,99% | [EINECS(EC#)]
608-667-5 | [Molecular Formula]
C21H20O5 | [MDL Number]
MFCD00078077 | [Molecular Weight]
352.38 | [MOL File]
31752-99-5.mol |
Questions And Answer | Back Directory | [Description]
(-)-Corey lactone 4-phenylbenzoate alcohol is one of the isomers of biphenyl-4-formylcorilactone, which can be used for the synthesis of prostaglandins. Prostaglandins are a class of important endogenous physiologically active substances, important mediators of various physiological processes, and have high pharmacological activity. Clinically, prostaglandins are all artificially synthesized. |
Chemical Properties | Back Directory | [Appearance]
Off-White to Pale Yellow Solid | [Melting point ]
131-132 °C(lit.)
| [alpha ]
-89 º (c=1, CHCl3) | [Boiling point ]
446°C (rough estimate) | [density ]
1.1818 (rough estimate) | [refractive index ]
1.5400 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
Chloroform, Ethyl Acetate | [form ]
Solid | [pka]
14.79±0.10(Predicted) | [color ]
Off-White to Pale Yellow | [optical activity]
[α]20/D 87°, c = 1 in chloroform | [Water Solubility ]
insoluble | [Usage]
Key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2a | [BRN ]
1294692 | [InChIKey]
SZJVIFMPKWMGSX-UHFFFAOYSA-N | [CAS DataBase Reference]
31752-99-5(CAS DataBase Reference) |
Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29322090 |
Hazard Information | Back Directory | [Chemical Properties]
Off-White to Pale Yellow Solid | [Uses]
(-) Corey lactone phenylbenzoate is a key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2α. |
|
|