| Identification | More | [Name]
(2S,4R)-4-METHYLGLUTAMIC ACID | [CAS]
31137-74-3 | [Synonyms]
SYM 2081
(2S,4R)-4-MethylglutamicAci
(2S-R)-4-METHYLGLUTAMIC ACID
(2S,4R)-4-METHYLGLUTAMIC ACID
(4R)- 4-Methyl-L-glutamic Acid
L-erythro--Methylglutamic Acid
erythro-L-4-Methylglutamic Acid
ERYTHRO-4-METHYL-L-GLUTAMIC ACID
L-Glutamic acid, 4-methyl-, (4R)-
(2S,4R)-4-METHYLGLUTAMIC ACID USP/EP/BP
(2S,4R)-(+)-2-Amino-4-methylpentanedioic acid
(2S,4R)-(+)-2-AMINO-4-METHYLPENTANEDIOIC ACID 99%
(2S,4R)-(+)-2-Amino-4-methylpentanedioic acid,99% | [Molecular Formula]
C6H11NO4 | [MDL Number]
MFCD00937765 | [Molecular Weight]
161.16 | [MOL File]
31137-74-3.mol |
| Chemical Properties | Back Directory | [Appearance]
White | [Melting point ]
178 °C | [Boiling point ]
287.44°C (rough estimate) | [density ]
1.3482 (rough estimate) | [refractive index ]
1.4230 (estimate) | [storage temp. ]
Store at RT | [solubility ]
H2O: >10 mg/mL
| [form ]
solid
| [pka]
2.34±0.21(Predicted) | [color ]
white
| [Usage]
A highly selective and potent agonist for kainate receptors. | [CAS DataBase Reference]
31137-74-3(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
White | [Uses]
A highly selective and potent agonist for kainate receptors. | [Biological Activity]
Potent and highly selective kainate receptor agonist, with an IC 50 for inhibition of [ 3 H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. Also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™ and Kainate Receptor Tocriset™ . | [storage]
Store at RT |
|
|