| Identification | Back Directory | [Name]
CIL56 | [CAS]
300802-28-2 | [Synonyms]
CA3
CIL56
CA3 NEW
CIL56(CA3)
YAP1 inhibitor CA3
CIL56;CIL-56;CIL 56;CA3;CA-3;CA 3
Recombinant Human CA3 Protein, His Tag
2,7-Bis-(piperidine-1-sulfonyl)-fluoren-9-one oxime
9H-Fluoren-9-one, 2,7-bis(1-piperidinylsulfonyl)-, oxime
N-Hydroxy-2,7-bis(1-piperidinylsulfonyl)-9H-fluoren-9-imine
7-bis(piperidin-1-ylsulfonyl)fluoren-9-ylidene]hydroxylamine
N-[2;7-BIS(PIPERIDIN-1-YLSULFONYL)FLUOREN-9-YLIDENE]HYDROXYLAMINE;CA3;CIL 56;CIL-56 | [Molecular Formula]
C23H27N3O5S2 | [MDL Number]
MFCD00323348 | [MOL File]
300802-28-2.mol | [Molecular Weight]
489.61 |
| Chemical Properties | Back Directory | [Boiling point ]
741.7±70.0 °C(Predicted) | [density ]
1.51±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml; Ethanol: 0.15 mg/ml | [form ]
A crystalline solid | [pka]
10.16±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CIL56 inhibits YAP/Tead transcriptional activity. Has anti-tumour effects on oesophageal adenocarcinoma with therapeutic potential in combination with 5-FU. Involved in ferroptosis, mediated by iron-dependent ROS. |
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