| Identification | More | [Name]
Prednisolone succinate | [CAS]
2920-86-7 | [Synonyms]
11-BETA,17-ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 21-HEMISUCCINATE
1,4-PREGNADIEN-11-BETA, 17,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE
1,4-PREGNADIEN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE
1,4-PREGNADIENE-11-BETA,17,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE
1-DEHYDROCORTISOL 21-HEMISUCCINATE
DELTA1-HYDROCORTISONE 21-HEMISUCCINATE
METACORTANDROLONE 21-HEMISUCCINATE
PREDNISOLONE 21-HEMISUCCINATE
PREDNISOLONE HEMISUCCINATE
PREDNISOLONE SUCCINATE
4-diene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-pregna-(1
prednisolonbisuccinat
prednisolone21-succinate
prednisolonebisuccinate
prednisolut
prednisolone 21-(hydrogen succinate)
D1-Hydrocortisone 21-hemisuccinate
Pregna-1,4-diene-3,20-dione, 11b,17,21-trihydroxy-, 21-(hydrogen succinate) (6CI, 7CI, 8CI)
Pregna-1,4-diene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11b)-(9CI)
Δ1-Hydrocortisone 21-hemisuccinate, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate, 1,4-Pregnadiene-11β,17,21-triol-3,20-dione 21-hemisuccinate | [EINECS(EC#)]
220-861-8 | [Molecular Formula]
C25H32O8 | [MDL Number]
MFCD00056465 | [Molecular Weight]
460.52 | [MOL File]
2920-86-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
206°C | [alpha ]
[α]D20 +99～+104゜ (c=0.5, 1,4-dioxane) | [Boiling point ]
485.35°C (rough estimate) | [density ]
1.1796 (rough estimate) | [refractive index ]
1.4480 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.29±0.17(Predicted) | [color ]
White to Off-White | [CAS DataBase Reference]
2920-86-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Risk Statements ]
R61:May cause harm to the unborn child.
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S53:Avoid exposure-obtain special instruction before use .
S22:Do not breathe dust .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [WGK Germany ]
3 | [RTECS ]
TU4153400 | [HS Code ]
2937290000 |
| Hazard Information | Back Directory | [Uses]
neuroleptic | [Uses]
Prednisolone hemisuccinate, is a metabolite of Prednisolone (P703740), which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. It is also the active metabolite of the drug prednisone. | [Definition]
ChEBI: Prednisolone succinate is a hemisuccinate resulting from the formal condensation of the 21-hydroxy group prednisolone with one of the carboxy groups of succinic acid. It is used to treat mild to moderate non-infectious eye allergies and inflammation, including damage caused by chemical and thermal burns. It has a role as an anti-inflammatory drug. It is a hemisuccinate, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a prednisolone and a succinic acid. It is a conjugate acid of a prednisolone succinate(1-). | [storage]
Store at -20°C |
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