| Identification | Back Directory | [Name]
(+)-DHMEQ | [CAS]
287194-41-6 | [Synonyms]
(1R,2R,6R)-DHMEQ
(1R,2R,6R)-Dehydroxymethylepoxyquinomicin
2-hydroxy-N-[(1R,2R,6R)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]benzamide
Benzamide, 2-hydroxy-N-[(1R,2R,6R)-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]- | [Molecular Formula]
C13H11NO5 | [MOL File]
287194-41-6.mol | [Molecular Weight]
261.23 |
| Chemical Properties | Back Directory | [Melting point ]
184 °C | [Boiling point ]
617.2±55.0 °C(Predicted) | [density ]
1.58±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 35 mg/mL (133.98 mM) | [form ]
Solid | [pka]
8.43±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
(+)-DHMEQ is an activator of the antioxidant transcription factor Nrf2. It is the enantiomer of (-)-DHMEQ. And it inhibited NF-kB activity less than (-)-DHMEQ. | [in vitro]
(+)-DHMEQ ((2R,3R,4R)-DHMEQ) activates Nrf2, which is a transcription factor that induces the expression of multiple antioxidant enzymes. (+)-DHMEQ activates Nrf2 in a promoter reporter assay. | [target]
| [storage]
Store at -20°C |
|
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