| Identification | Back Directory | [Name]
1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE | [CAS]
284028-90-6 | [Synonyms]
DR 2313
IR 2313
SC-202756
DR2313 >=98% (HPLC)
PARP Inhibitor XI, DR2313
4H-Thiopyrano[4,3-d]pyriMidin-4-one,3,5,7,8-tetrahydro-2
7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one
3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
2-Methyl-1-sulfanyl-1H,4H,5H,7H,8H-pyrano[4,3-d]pyriMidin-4-one
4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE,3,5,7,8-TETRAHYDRO-2-METHYL-
3,5,7,8-tetrahydro-2-methyl-4h-thiopyrano(4,3-d)pyrimidin-4-one, 98%(HPLC) | [EINECS(EC#)]
200-589-5 | [Molecular Formula]
C8H10N2OS | [MDL Number]
MFCD08703132 | [MOL File]
284028-90-6.mol | [Molecular Weight]
182.24 |
| Chemical Properties | Back Directory | [Boiling point ]
349.3±52.0 °C(Predicted) | [density ]
1.46±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
H2O: >2mg/mL (warmed) | [form ]
powder | [pka]
1.54±0.20(Predicted) | [color ]
white to beige | [Water Solubility ]
H2O: >2mg/mL (warmed) |
| Hazard Information | Back Directory | [Biological Activity]
Potent, competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC 50 values are 0.20 and 0.24 μ M for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro . Brain penetrant. |
|
| Company Name: |
|
| Tel: |
821-50328103-801 18930552037 |
| Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList13285/0.htm |
| Company Name: |
China Langchem Inc.
|
| Tel: |
0086-21-58956006 |
| Website: |
www.approvedhomemanagement.com/ShowSupplierProductsList19141/0.htm |
|