| Identification | Back Directory | [Name]
Masoprocol | [CAS]
27686-84-6 | [Synonyms]
CHX-100
masoprocol
NORHYDROGUAIARETICACID
Masoprocol(nordihydroguaiaretic)
meso-4，4'-(2，3- Dimethyltetramethylene)dipyrocatechol
(R*,S*)-4,4'-(2,3-dimethylbutane-1,4-diyl)bispyrocatechol
4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol
4,4'-((2R,3S)-2,3-DiMethylbutane-1,4-diyl)bis(benzene-1,2-diol)
4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyrocatechol
rel-4,4'-((2R,3S)-2,3-Dimethylbutane-1,4-diyl)bis(benzene-1,2-diol)
4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]benzene-1,2-diol | [EINECS(EC#)]
248-606-6 | [Molecular Formula]
C18H22O4 | [MDL Number]
MFCD00866548 | [MOL File]
27686-84-6.mol | [Molecular Weight]
302.365 |
| Hazard Information | Back Directory | [Description]
Masoprocol is a lipoxygenase inhibitor launched as a topical agent for the treatment of
solar or actinic keratoses. It is the first new topical treatment for pre-malignant skin
lesions introduced in twenty years. Masoprocol is obtained from the Larrea tridentata
plant and is also under investigation for the treatment of lung, breast, colon and ovarian cancers. | [Originator]
Chemex (U.S.A.) | [Uses]
Antineoplastic. | [Definition]
ChEBI: Masoprocol is the meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. It has a role as an antineoplastic agent, a lipoxygenase inhibitor, a hypoglycemic agent and a metabolite. | [Brand name]
Actinex (University Of Arizonia Cancer Center). |
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BOC Sciences
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NCE Biomedical Co.,Ltd.
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AmplaChem, Inc.
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www.amplacheminc.com |
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