| Identification | More | [Name]
5-NITRO-2-FUROYL CHLORIDE | [CAS]
25084-14-4 | [Synonyms]
5-NITRO-2-FUROYL CHLORIDE
5-NITROFURAN-2-CARBONYL CHLORIDE
2-Furancarbonyl chloride, 5-nitro-
2-Furoyl chloride, 5-nitro-
5-nitrofuroyl chloride
5-Nitro-2-furancarbonyl chloride
5-Nitro-2-furoyl chloride, predominantly trans, 97% | [EINECS(EC#)]
246-607-6 | [Molecular Formula]
C5H2ClNO4 | [MDL Number]
MFCD00039564 | [Molecular Weight]
175.53 | [MOL File]
25084-14-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
3261 | [WGK Germany ]
3 | [Hazard Note ]
Corrosive | [HazardClass ]
8 | [PackingGroup ]
II |
| Hazard Information | Back Directory | [Description]
5-Nitrofuroyl chloride is a furan chain bound to an acyl and
a nitro group. Nitrofuran derivatives have been used as
antibiotic and antimicrobial drugs but the acyl group bound
to furan (furoyl chloride) is an intermediate for the synthesis
of pharmaceuticals (e.g. antibiotics). 5-Nitrofuroyl chloride
has been used as a reagent for the synthesis of some
compounds with antibacterial properties and other
chemicals. | [Uses]
5-Nitro-2-furoyl Chloride is used as reactant in the synthesis of several therapeutic agents. | [Uses]
5-Nitrofuroyl chloride has been used in the synthesis of certain
ureides of furanmonocarboxylic acid and in the synthesis of
two salts of the mesoionic compound with an influence on the
effectiveness of norfloxacin, tetracycline, and erythromycin.
There is a study on the antibacterial effects of some 5-nirtofuroyl
derivatives but not on 5-nitrofuroyl chloride. There are
no reports on its commercial use. | [Environmental Fate]
5-Nitrofuroyl chloride is a colorless crystal with molecular
weight of 175.53 g mol-1. It is stable under normal temperature
and pressure on the basis of its melting point (38–14℃).
There are no available data on its solubility in water. The bioaccumulation
factor (BCF) for this compound is 4.29 at pH 7.4,
which indicates low accumulation in aquatic organisms. The
soil adsorption coefficient normalized to the content of organic
carbon (Koc value) is 98.92 at pH 7.4, which indicates high
mobility in soil. |
|
| Company Name: |
Alfa Aesar
|
| Tel: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|