| Identification | Back Directory | [Name]
(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate | [CAS]
250159-48-9 | [Synonyms]
Miriplatin hydrate
Miriplatin monohydrate
(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate | [Molecular Formula]
C34H70N2O5Pt | [MDL Number]
MFCD22572709 | [MOL File]
250159-48-9.mol | [Molecular Weight]
782.008 |
| Hazard Information | Back Directory | [Biological Activity]
Miriplatin hydrate (SM-11355 hydrate) is an effective chemotherapeutic agent and is a kind of alkylator. | [in vitro]
Miriplatin suspended in lipiodol (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis. | [in vivo]
Miriplatin (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells. | [storage]
Store at -20°C |
|
|