Identification | Back Directory | [Name]
2,6-Dioxopiperidine-3-ammonium chloride | [CAS]
24666-56-6 | [Synonyms]
Pomalidomide Impurity 6 Lenalidomide Impurity 6 6-piperidinedione hydrochloride 3-AMino-2,6-Piperidinedione HCl Glutamic acid imide hydrochloride 2-Amino-glutarimide Hydrochloride DL-Glutamic Acid Imide Hydrochloride 2,6-dioxopiperidin-3-aminium chloride 2,6-Dioxopiperidine-3-ammonium chloride 3-amino piperdine-2,6-dion hydrochloride 3-Amino-2,6-piperidinedione hydrochloride 3-AMino-2,6-dioxo-piperidine hydrochloride 3-Aminopiperidine-2,6-dione Monohydrochloride 2,6-Piperidinedione, 3-amino-, hydrochloride 3-Amino-2,6-dioxo-piperidine hydrochloride ,99% 2,6-Piperidinedione,3-aMino-, hydrochloride (1:1) 2,6-Dioxopiperidine-3-ammonium chloride###3-aminopiperidine-2,6-dione hydrochloride | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C5H9ClN2O2 | [MDL Number]
MFCD11042437 | [MOL File]
24666-56-6.mol | [Molecular Weight]
164.59 |
Hazard Information | Back Directory | [Chemical Properties]
White crystal | [Uses]
2,6-Dioxopiperidine-3-ammonium chloride can be used as an important intermediate of antineoplastic drug lenalidomide.
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Questions And Answer | Back Directory | [Description]
2,6-Dioxopiperidine-3-ammonium chloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del (5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Moreover, it is also a metabolite of thalidomide (T338850) that inhibits FGF-induced angiogenesis.
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