| Identification | Back Directory | [Name]
N-(1-oxohexyl)-glycine | [CAS]
24003-67-6 | [Synonyms]
NSC 224460
Caproylglycine
Hexanoylglycine
N-caproylglycine
(Hexanol Glycine)
n-Hexanoylglycine
N-(1-oxohexyl)-glycine
Glycine, N-(1-oxohexyl)-
Hexanoyl Glycine (NSC 224460) | [Molecular Formula]
C8H15NO3 | [MDL Number]
MFCD09909949 | [MOL File]
24003-67-6.mol | [Molecular Weight]
173.21 |
| Chemical Properties | Back Directory | [Melting point ]
90-92°C | [Boiling point ]
387.2±25.0 °C(Predicted) | [density ]
1.074±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
3.60±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
Hexanoyl glycine is an acylated amino acid that is used as a urinary biomarker for several indications. It is normally biosynthesized from hexanoyl-CoA and glycine by the mitochondrial enzyme glycine N-acyltransferase. Increased urinary excretion of hexanoyl glycine in humans is indicative of a deficiency in medium-chain acyl-CoA dehydrogenase. Increased urinary hexanoyl glycine can also be used as a biomarker for exposure to gamma radiation. Levels of hexanyl glycine can also be elevated during cancer, while they are decreased 20-fold in mice following treatment with the PPARα ligand Wy 14643. | [Chemical Properties]
White Solid | [Uses]
An acylaminoacid derivative as antipsychotic drug | [Uses]
An acylaminoacid derivative as antipsychotic drug. | [Definition]
ChEBI: An N-acylglycine in which the acyl group is specified as hexanoyl. |
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