Identification | Back Directory | [Name]
PALMITOYL CARNITINE | [CAS]
2364-67-2 | [Synonyms]
C02990 Palmitylcarnitine Palmityl-L-carnitine L-Palmitoylcarnitine Hexadecanoylcarnitine Palmitoyl L-carnitine O-palmitoyl-L-carnitine Palmitoyl-L-Carnitine solution Palmitoyl-L-carnitine >=97.0% (TLC) (3R)-3-hexadecanoyloxy-4-trimethylazaniumylbutanoate (-)-[(R)-3-Carboxylato-2-(palmitoyloxy)propyl]trimethylaminium (2R)-3-Carboxylato-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-1-propanaminium 1-PropanaMiniuM, 3-carboxy-N,N,N-triMethyl-2-[(1-oxohexadecyl)oxy]-, inner salt, (2R)- | [Molecular Formula]
C23H45NO4 | [MDL Number]
MFCD00152152 | [MOL File]
2364-67-2.mol |
Hazard Information | Back Directory | [Uses]
L-?Palmitoyl Carnitine is used as a diagnostic agent in the investigation of drug toxicity with respect to the liver. Acts as a biomarker in the study of metabolism in metabolic diseases. | [Definition]
ChEBI: An O-acyl-L-carnitine in which the acyl group is specified as palmitoyl (hexadecanoyl). | [General Description]
Palmitoyl-L-carnitine (PLC) belongs to the class of long chain acylcarnitine compounds. It is an acyl-chain ester, which can be obtained from L-carnitine via acylcarnitine family transferase. PLC is reported to be used for the phospholipid reacylation in erythrocyte membrane ghosts. | [Biochem/physiol Actions]
L-Palmitoylcarnitine can change the activity of several enzymes and transporters, localized in the membrane and facilitates the transfer of long-chain fatty acids from cytoplasm into mitochondria during the oxidation of fatty acids. L-Palmitoylcarnitine accumulates in ischemic myocardium and potentially contribute to myocardial damage through alterations in membrane molecular dynamics. |
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