| Identification | More | [Name]
2,4-Thiazolidinedione | [CAS]
2295-31-0 | [Synonyms]
1,3-THIAZOLIDINE-2,4-DIONE
2,3,4,5-TETRAHYDROTHIAZOLE-2,4-DIONE
2,4-DIKETOTHIAZOLIDINE
2,4-THIAZOLIDINEDIONE
AKOS B029064
AURORA 23272
OTAVA-BB BB7112440002
THIAZOLIDINE-2,4-DIONE
TIMTEC-BB SBB000047
TZD
2,4(3H,5H)-Thiazoledione
2,4-Dioxothiazolidine
Thiazolidinedione
Thiazolidinedione-2,4
USAF ek-5496
usafek-5496
2,4-Thiadolidinedione
2,4-Thiazolinedione
2,4-THIAZOLIDINEDIONE, TECH., 90%
2,4-Thiazolidindione | [EINECS(EC#)]
218-941-2 | [Molecular Formula]
C3H3NO2S | [MDL Number]
MFCD00005478 | [Molecular Weight]
117.13 | [MOL File]
2295-31-0.mol |
| Chemical Properties | Back Directory | [Appearance]
White to Off-White Powder | [Melting point ]
125-127 °C (lit.) | [Boiling point ]
178-179 °C (19 mmHg)
| [density ]
1.408 (estimate) | [vapor pressure ]
0Pa at 25℃ | [refractive index ]
1.5130 (estimate) | [Fp ]
178-179°C/19mm | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Crystalline Powder | [pka]
6.50±0.10(Predicted) | [color ]
Slightly yellow | [Water Solubility ]
Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether. | [Usage]
Inhibitor of enzyme | [Detection Methods]
HPLC,NMR | [BRN ]
110700 | [InChIKey]
ZOBPZXTWZATXDG-UHFFFAOYSA-N | [LogP]
-0.29 at 25℃ | [CAS DataBase Reference]
2295-31-0(CAS DataBase Reference) | [NIST Chemistry Reference]
2,4-Thiazolidinedione(2295-31-0) | [EPA Substance Registry System]
2295-31-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
XJ5775000
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
IRRITANT | [HS Code ]
29341000 |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Powder | [Uses]
Inhibitor of enzyme | [Definition]
ChEBI: A thiazolidenedione carrying oxo substituents at positions 2 and 4. | [General Description]
2,4-Thiazolidinedione is a well-known peroxisome proliferator-activated receptors (PPAR) activator. Its effect on aging process using kidneys from Fischer 344 rats has been reported. A library of conjugates of 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C catalyst. Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione in polyethylene glycol-300 has been reported. | [Flammability and Explosibility]
Notclassified |
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