| Identification | Back Directory | [Name]
(2-pyridyldithio)-PEG4-propargyl | [CAS]
2170240-99-8 | [Synonyms]
(2-pyridyldithio)-PEG4-propargyl | [Molecular Formula]
C16H23NO4S2 | [MDL Number]
MFCD31580154 | [MOL File]
2170240-99-8.mol | [Molecular Weight]
357.49 |
| Chemical Properties | Back Directory | [Boiling point ]
465.6±45.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [form ]
Liquid | [pka]
1.81±0.12(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
(2-pyridyldithio)-PEG4-propargyl is a PEG linker which contains a pyridyl disulfide moiety and a propargyl group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH levels. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media. |
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