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ChemicalBook--->CAS DataBase List--->1334177-95-5

1334177-95-5

1334177-95-5 Structure

1334177-95-5 Structure
IdentificationBack Directory
[Name]

SPDP-PEG4-NHS ester
[CAS]

1334177-95-5
[Synonyms]

4-NHS ester
SPDP-dPEG®
SDPD-PEG4-NHS
NHS-PEG4-SPDP
SPDP-PEG4-NHS
Opss-peg(4)-nhs
SPDP-PEG4-NHS ester
SPDP-dPEG??-NHS ester
SPDP-dPEG(R)4-NHS ester
3-(2-Pyridyldithio)propionamido-PEG4-NHS Ester
N-Succinimidyl 3-Oxo-1-(pyridin-2-yldisulfanyl)-7,10,13,16-tetraoxa-4-azanonadecan-19-oate
3-Oxo-1-(pyridin-2-yldisulfanyl)-7,10,13,16-tetraoxa-4-azanonadecan-19-oic Acid N-Succinimidyl Ester
4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 17-oxo-19-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-(pyridin-2-yldisulfanyl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
[Molecular Formula]

C23H33N3O9S2
[MDL Number]

MFCD13185001
[MOL File]

1334177-95-5.mol
[Molecular Weight]

559.65
Chemical PropertiesBack Directory
[density ]

1.34±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Soluble in DMSO, DCM, DMF
[form ]

solid or viscous liquid
[pka]

15.01±0.46(Predicted)
[color ]

White or Colorless to Almost white or Almost colorless
[Water Solubility ]

water: soluble
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[HS Code ]

2933.39.9200
Hazard InformationBack Directory
[Description]

SPDP-PEG4-NHS ester is a PEG linker containing an SPDP crosslinker and an NHS ester. The SPDP crosslinker is reactive toward amine and thiol groups and contains a cleavable disulfide bond. This crosslinker is also membrane permeable which allows for intracellular reactions to take place. The NHS ester can react with primary amines to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
[reaction suitability]

reagent type: cross-linking reagent
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