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ChemicalBook--->CAS DataBase List--->21003-46-3

21003-46-3

21003-46-3 Structure

21003-46-3 Structure
IdentificationBack Directory
[Name]

Prostaglandin E1 Impurity 4
[CAS]

21003-46-3
[Synonyms]

8-Iso-PGE1
OVINONIC ACID
(-)-8-epi-PGE1
8-Epiprostaglandin E1
8-epi-Prostaglandin E1
8-ISO PROSTAGLANDIN E1
Alprostadil EP Impurity F
GMVPRGQOIOIIMI-JCPCGATGSA-N
Prostaglandin (Alprostadil) EP Impurity F
9-oxo-11α,15S-dihydroxy-(8β)-prost-13E-en-1-oic acid
(8β,13E,15S)-11α,15-Dihydroxy-9-oxoprost-13-en-1-oic acid
9-Oxo-11aloha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid
9-OXO-11ALPHA,15S-DIHYDROXY-(8BETA)-PROST-13E-EN-1-OIC ACID
Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (8β,11α,13E,15S)-
7-[(1S,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
f.7-[(1S,2R,3R)-3-hydroxy-2-[(1e,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoicacid(8-epiprostaglandine1),
[Molecular Formula]

C20H34O5
[MDL Number]

MFCD00065736
[MOL File]

21003-46-3.mol
[Molecular Weight]

354.48
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
[form ]

A light yellow crystalline solid
Hazard InformationBack Directory
[Description]

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF.
[Uses]

8-Isoprostaglandin E1 has vasodilatory and electrophysiological actions porcine coronary artery. It also inhibits acetylcholine release from parasympathetic nerves innervating guinea-pig trachea mediation by prostanoid EP3 receptors.
[Uses]

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α.[Cayman Chemical]
[Definition]

ChEBI:8-Isoprostaglandin E1 is a prostanoid.
[storage]

Store at -20°C
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